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Sackler School of Graduate Biomedical Sciences

Amy Yee

What is the ultimate goal of your research?
We investigate breast cancer mechanisms. Our research combines clinical and molecular approaches to identify new prognostic markers and therapeutic targets for early breast cancers. Breast cancer is a disease with an often uncertain prognosis. Our research focuses upon basic and translational applications to achieve the goal of improving patient outcome. We have identified the HBP1 transcriptional repressor and cell cycle regulator as a key factor for invasive breast cancer. Using the knowledge of molecular signaling pathways and clinically relevant models, we focus also on how nutritional compounds can be developed for breast cancer treatment and prevention.

What excites you about your research?
I want to make a difference in the lives of breast cancer patients and improve patient outcome by making the insights that will lead to therapies for definitive treatment of breast cancer and prevent the fatal recurrences. I like the combination of molecular and clinical aspects of breast cancer in my research. I firmly believe that the appreciation for clinical outcomes enriches the lab-based experiments.

What do you like best about Sackler students?
Sackler students are bright, hard working, and enthusiastic about research. I teach a core Sackler course and enjoy their sophisticated thinking abilities.

What qualities distinguish the Sackler School from other graduate schools?
We have an exceptional dedication to PhD training. The Sackler School is an amalgam of different graduate programs that reflect our varied research interests. The entire faculty is motivated to provide the best possible training in the graduate programs. We all wish for the students to flourish in graduate school and in their future career. A unique aspect is a collegiality that crosses departments and programs—a feature that enriches the training experience for students.

What do you do to relax?
I like to play tennis and to follow those Boston Red Sox.

What is your favorite Boston restaurant?
Blue Ginger

Amy Yee
Home Town: San Francisco, CA
Prior Degrees: 
AB, Biochemistry, University of California, Berkeley
PhD, Biochemistry, University of California, Davis