What’s the ultimate goal of your research?
My group seeks to identify early causative events that underlie cognitive deficits associated with ‘normal’ aging and Alzheimer’s disease. We are also interested in understanding factors that appear to protect some individuals from developing Alzheimer's disease against a genetic background that carries mutations known to cause the disease.
What excites you about your research?
Our work uses sophisticated computational and statistical methods to merge knowledge from our mouse experiments with human data as well as combining systems genetics with innovative high resolution and high throughput membrane proteomics, viral-based gene transduction approaches, behavioral assays and electrophysiology. This provides the best chance of discovery novel therapeutic targets to promote brain resilience that are going to translate to humans.
What do you like best about Sackler students?
They are a very savvy group, well-versed in technology and skills to work with big data. I really value their creativity and motivation – I’m impressed by how supportive they are of each other, and how well they engage faculty and collaborators.
What qualities distinguish the Sackler School from other graduate schools?
Strong cross-disciplinary research, world class neurogenetics resources and platforms, access to world class courses and conferences at The Jackson Laboratory.
What do you do to relax?
TGIF at The Jackson Laboratory and hiking.
What is your favorite local restaurant?
Havana, Bar Harbor