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Sackler School of Graduate Biomedical Sciences

Alexei Degterev

What is the ultimate goal of your research?

The goal of our work is to better understand how aberrant regulation of cell death contributes to human disease. We start from cellular models of cell death in vitro, focusing on the basic mechanisms of various forms of cell death, and try to translate our findings to the relevant animal models of human disease. Another important goal of our work is to develop novel small molecule modulators of cell death, which can be useful both as research tools in vitro and in vivo and as lead molecules for new therapies.

What excites you about your research?

The possibility of translating discoveries related to the fundamental modes of cellular regulation into new and important insights of human disease is a driving force.

What do you like best about Sackler students?

Sackler students are bright, hard working and pleasure to interact with. Because of the interdisciplinary nature of the ISP program, students usually have a genuine curiosity in many areas of research and are not afraid to expand studies beyond their immediate focus area. Students are real drivers of the research at Tufts.

What qualities distinguish the Sackler School from other graduate schools?

The openness of the faculty to scientific discussion and new collaborations, bridging different areas of research is an important hallmark of Sackler.

What do you do to relax?

I relax by spending time with my family, going to the gym, cycling and skiing. I also enjoy listening to music and reading.

What is your favorite local restaurant?

I really like the Public House in Brookline. It is one of the best beer restaurants in the US and I am a big fan of Belgian beers.

Alexei Degterev
Home Town: Moscow, Russia
Prior Degrees: 
BS, Chemistry, Moscow State University
MS, Biochemistry, Moscow State University
PhD, Biochemistry, Boston University