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Sackler School of Graduate Biomedical Sciences

Recent Publications from the G Sonenshein Lab

de la Cueva A, Emmerling M, Lim SL, Yang S, Trackman PC, Sonenshein GE, Kirsch KH. 2018. A polymorphism in the lysyl oxidase propeptide domain accelerates carcinogen-induced cancer. Carcinogenesis Epub ahead of print. Abstract

Sánchez-Morgan N, Kirsch KH, Trackman PC, Sonenshein GE. 2017. UXT is a LOX-PP interacting protein that modulates estrogen receptor Alpha activity in breast cancer cells. J Biol Chem. Epub ahead of print. Abstract

Lyons J, Polmear M, Mineva ND, Romagnoli M, Sonenshein GE, Georgakoudi I. 2016. Endogenous light scattering as an optical signature of circulating tumor cell clusters. Biomed Opt Express 7: 1042-1050. Abstract

Das SG, Romagnoli M, Mineva ND, Barillé-Nion S, Jézéquel P, Campone M, Sonenshein GE. 2016. miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells. Breast Cancer Res. 18:40. Abstract

Srinivasan S, Romagnoli M, Bohm A, Sonenshein GE. 2014. N-Glycosylation regulates ADAM8 processing and activation. J Biol Chem. 289: 33676-33688. Abstract

Bais MV, Ozdener GB, Sonenshein GE, Trackman PC. 2014. Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways. Oncogene 34: 1928-1937. Abstract

Romagnoli M, Mineva ND, Polmear M, Conrad C, Srinivasan S, Loussouarn D, Barillé-Nion S, Georgakoudi I, Dagg A, McDermott EW, Duffy MJ, McGowan PM, Schlomann U, Parsons M, Bartsch JW, Sonenshein GE. 2013. ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis. EMBO Mol Med. 6: 278-294. Abstract

Sato S, Zhao Y, Imai M, Simister PC, Feller SM, Trackman PC, Kirsch KH, Sonenshein GE. 2013. Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide. PLoS One 8: e77288. Abstract

Mineva ND, Paulson KE, Naber SP, Yee AS, Sonenshein GE. 2013. Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells. PLoS One 8: e73464. Abstract

Romagnoli M, Belguise K, Yu Z, Wang X, Landesman-Bollag E, Seldin DC, Chalbos D, Barillé-Nion S, Jézéquel P, Seldin ML, Sonenshein GE. 2012. Epithelial-to-mesenchymal transition induced by TGF-β1 is mediated by Blimp-1-dependent repression of BMP-5. Cancer Res. 72: 6268-6278. Abstract

Yu Z, Sato S, Trackman PC, Kirsch KH, Sonenshein GE. 2012. Blimp1 activation by AP-1 in human lung cancer cells promotes a migratory phenotype and is inhibited by the lysyl oxidase propeptide. PLoS One 7: e33287. Abstract

Bais MV, Nugent MA, Stephens DN, Sume SS, Kirsch KH, Sonenshein GE, Trackman PC. 2012. Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts. PLoS One. 7: e31188. Abstract