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Sackler School of Graduate Biomedical Sciences

Lucy Liaw

Professor of Medicine
Lucy Liaw

Lucy Liaw

Professor of Medicine

Office phone: 207-396-8142
Lab phone: 207-396-8177
Email: liawl@mmc.org
Campus: MMCRI, Scarborough, Maine
Laboratory: 
20325 & 20326
Education: 
BS, Biology, University of Arizona
PhD, Biological Structure, University of Washington, Seattle
Postdoctoral Training, Vanderbilt University
Research synopsis: 

My laboratory has extensive experience studying signaling in vascular disease, with an emphasis on smooth muscle biology during injury and pathology. Recently, we extended our focus to include study of perivascular adipose tissue (PVAT), which is essential in providing a specialized microenvironment for blood vessels. PVAT is contiguous with the vascular adventitia, providing a local source of secreted adipokines that act directly on the vessel wall. Our research vision is to characterize the molecular changes that occur in PVAT and the underlying blood vessel during metabolic dysfunction, which collectively lead to susceptibility to cardiovascular disease. We aim to translate this understanding by testing human PVAT and blood vessels to validate biomarkers of vascular disease susceptibility, identify novel therapeutic targets, and gain mechanistic understanding of PVAT dysfunction. Our discoveries will provide innovative advances for cardiovascular science and clinical care.

Lab members: