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Student Publications

Publication in peer-reviewed journals is a very important part of graduate training. Publications by Neuroscience students over the past five years are listed below. The names of student authors are in bold font.

2019

Hanson E, Armbruster M, Lau LA, Sommer ME, Klaft ZJ, Swanger SA, Traynelis SF, Moss SJ, Noubary F, Chadchankar J, Dulla CG. 2019. Tonic activation of GluN2C/GluN2D-containing NMDA receptors by ambient glutamate facilitates cortical interneuron maturation. J Neurosci. Epub ahead of print.  Abstract

2018

Barrios-Camacho CM. 2018. Expression of bona fide epithelial stem cell marker in postmitotic olfactory bulb neurons suggest novel roles for Wnt signaling in the brain. J Neurosci. 38: 2920-2922.  Abstract

Coleman A, Biederer T. 2018. Open up to make new contacts: Caldendrin senses postsynaptic calcium influx to dynamically organize dendritic spines. Neuron 97: 994-996.  Abstract

Coleman JH, Lin B, Louie JD, Peterson J, Lane RP, Schwob JE. 2018. Spatial determination of neuronal diversification in the olfactory epithelium. J Neurosci. Epub ahead of print. Abstract

Dickson DA, Paulus JK, Mensah V, Lem J, Saavedra-Rodriguez L, Gentry A, Pagidas K, Feig LA. 2018. Reduced levels of miRNAs 449 and 34 in sperm of mice and men exposed to early life stress. Transl Psychiatry 8: 101. Abstract

Hines RM, Maric HM, Hines DJ, Modgil A, Panzanelli P, Nakamura Y, Nathanson AJ, Cross A, Deeb T, Brandon NJ, Davies P, Fritschy JM, Schindelin H, Moss SJ. 20018. Developmental seizures and mortality result from reducing GABAA receptor α2-subunit interaction with collybistin. 2018. Nat Commun. 9: 3130. Abstract

Hooper A, Fuller PM, Maguire J. 2018. Hippocampal corticotropin-releasing hormone neurons support recognition memory and modulate hippocampal excitability. PLoS One 13: e0191363. Abstract

Kelley KW, Ben Haim L, Schirmer L, Tyzack GE, Tolman M, Miller JG, Tsai HH, Chang SM, Molofsky AV, Yang Y, Patani R, Lakatos A, Ullian EM, Rowitch DH. 2018. Kir4.1-dependent astrocyte-fast motor neuron interactions are required for peak strength. Neuron 98: 306-319. Abstract

Koenig JB, Dulla CG 2018. Dysregulated glucose metabolism as a therapeutic target to reduce post-traumatic epilepsy. Front Cell Neurosci. doi: 10.3389/fncel.2018.00350.  Abstract

Kuo YC, He X, Coleman AJ, Chen YJ, Dasari P, Liou J, Biederer T, Zhang X. 2018. Structural analyses of FERM domain-mediated membrane localization of FARP1. Sci Rep. 8: 10477.  Abstract

von Mässenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, Bach S, Schiessl IM, Nogusa S, Balachandran S, Anders HJ, Ting AT, Bleich M, Degterev A, Kunzelmann K, Bornstein SR, Green DR, Hugo C, Linkermann A. 2018. Phenytoin inhibits necroptosis. Cell Death Dis. 9:359. Abstract

Pirone A, Alexander JM, Koenig JB, Cook-Snyder DR, Palnati M, Wickham RJ, Eden L, Shrestha N, Reijmers L, Biederer T, Miczek KA, Dulla CG, Jacob MH. 2018. Social stimulus causes aberrant activation of the medial prefrontal cortex in a mouse model with autism-like behaviors. Fron Synaptic Neurosci. Epub ahead of print.  Abstract

Rifkin RA, Huyghe D, Li X, Parakala M, Aisenberg E, Moss SJ, Slesinger PA. 2018. GIRK currents in VTA dopamine neurons control the sensitivity of mice to cocaine-induced locomotor sensitization. Proc Natl Acad Sci USA Epub head of print. Abstract

Saleh D, Degterev A. 2018. Chemical library screens to identify pharmacological modulators of necroptosis. Methods Mol Biol. 1857: 19-33. Abstract

Shih J, Dulla CG. 2018. The THIK and thin of microglia dynamics. Neuron 97: 253-255. Abstract

You S, Fulga TA, Van Vactor D, Jackson FR. 2018. Regulation of circadian behavior by astroglial microRNAs in Drosophila. Genetics 208: 1195-1207.  Abstract

Xu J*, Bartolome CL*, Low CS, Yi X, Chien CH, Wang P, Kong D. 2018. Genetic identification of leptin neural circuits in energy and glucose homeostases. Nature 556: 505-509. *equal contribution Abstract

2017

Coleman JH, Lin B, Schwob JE. 2017. Dissecting LSD1-dependent neuronal maturation in the olfactory epithelium. J Comp Neurol. 525: 3391-3413. Abstract

Davis P, Reijmers LG. 2017. The dynamic engram: fear memories and the basolateral amygdala. Brain Res Bull. Epub ahead of print.  Abstract

Davis P, Zaki Y, Maguire J, Reijmers LG 2017. Cellular and oscillatory substrates of fear extinction learning. Nat Neurosci. 20: 1624-1633. Abstract

Felsted JA, Chien CH, Wang D, Panessiti M, Ameroso D, Greenberg A, Feng G, Kong D, Rios M. 2017. Alpha2delta-1 in SF1+ neurons of the ventromedial hypothalamus is an essential regulator of glucose and lipid homeostasis. Cell Rep. 21: 2737-2747. Abstract

Foley J, Blutstein T, Lee S, Erneux C, Halassa MM, Haydon P. 2017. Astrocytic IP3/Ca2+ signaling modulates theta rhythm and REM sleep. Front Neural Circuits 11:3.  Abstract

Fuchs T, Jefferson SJ, Hooper A, Yee PP, Maguire J, Luscher B. 2017. Disinhibition of somatostatin-positive interneurons by deletion of postsynaptic GABAA receptors. Mol Psychiatry 22: 787. Abstract

Hodul M, Dahlberg CL, Juo P. 2017. Function of the deubiquitinating enzyme USP46 in the nervous system and its regulation by WD40-repeat proteins. Front Synaptic Neurosci. 9:16. Abstract

Hooper A, Paracha R, Maguire J.. 2017. Seizure-induced activation of the HPA axis increases seizure frequency and comorbid depression-like behaviors. Epilepsy Behav. 78: 124-133. Abstract

Jones A, Reijmers LG. 2017. Mapping brain activity onto molecularly defined cells. Neuron 96:248-249. Abstract

Lau LA, Noubary F, Wang D, Dulla CG. 2017. α2δ-1 signaling drives cell death, synaptogenesis, circuit reorganization, and gabapentin-mediated neuroprotection in a model of insult-induced cortical malformation. eNeuro eCollection Sept-Oct.  Abstract

Lin B, Coleman JH, Peterson JN, Zunitch MJ, Jang W, Herrick DB, Schwob JE. 2017. Injury induces endogenous reprogramming and dedifferentiation of neuronal progenitors to multipotency. Cell Stem Cell 21: 761-774 . Abstract

Melón LC, Hooper A, Yang X, Moss SJ, Maguire J. 2017. Inability to suppress the stress-induced activation of the HPA axis during the peripartum period engenders deficits in postpartum behaviors in mice. Psychoneuroendocrinology 90: 182-193. Abstract

Moore YE, Kelley MR, Brandon NJ, Deeb TZ, Moss SJ. 2017. Seizing control of KCC2: A new therapeutic target for epilepsy. Trends Neurosci. 40: 555-571.  Abstract

Papouin T, Dunphy J, Tolman M, Foley JC, Haydon PG. 2017. Astrocytic control of synaptic function. Philos Trans R Soc Lond B Biol Sci. 372 (1715). Abstract

Papouin T, Dunphy JM, Tolman M, Dineley KT, Haydon PG. 2017. Septal cholinergic neuromodulation tunes the astrocyte-dependent gating of hippocampal NMDA receptors to wakefulness. Neuron 94: 840-854. Abstract

Saleh D, Najjar M, Zelic M, Shah S, Nogusa S, Polykratis A, Paczosa MK, Gough PJ, Bertin J, Whalen M, Fitzgerald KA, Slavov N, Pasparakis M, Balachandran S, Kelliher M, Mecsas J, Degterev A. 2017. Kinase activities of RIPK1 and RIPK3 can direct IFN-β synthesis induced by lipopolysaccharide. J Immunol. 198: 4435-4447.  Abstract

Salzberg Y, Coleman A, Celestrin K, Cohen-Berkman M, Biederer T, Henis-Korenblit S, Bulow HE. 2017. Reduced insulin/insulin-like growth factor receptor signaling mitigates defective dendrite morphogenesis in mutants of the ER stress senor IRE-1. PLoS Genet. 13: e1006579.  Abstract

Wegner KW, Saleh D, Degterev A. 2017. Complex pathologic roles of RIPK1 and RIPK3: Moving beyond necroptosis. Trends Pharmacol Sci. 28: 202-225.  Abstract

2016

Armbruster M, Hanson E, Dulla CG. 2016. Glutamate clearance is locally modulated by presynaptic neuronal activity in the cerebral cortex. J Neurosci. 36: 10404-10415.   Abstract

Cairns DM, Chwalek K, Moore YE, Kelley MR, Abbott RD, Moss S, Kaplan DL. 2016. Expandable and rapidly differentiating human induced neural stem cell lines for multiple tissue Engineering applications. Stem Cell Rep. 7: 557-570. Abstract

Clasadonte J, Morel L, Barrios-Camacho CM, Chiang MS, Zhang J, Iyer L, Haydon PG, Yang Y. 2016. Molecular analysis of acute and chronic reactive astrocytes in the pilocarpine model of temporal lobe epilepsy. Neurobiol Dis. 91: 315-325. Abstract

Hanson E, Danbolt NC, Dulla CG. 2016. Astrocyte membrane properties are altered in a rat model of developmental cortical malformation but single-cell astrocytic glutamate uptake is robust. Neurobiol Dis. 89: 157-168.  Abstract

Hooper A, Maguire J 2016. Characterization of a novel subtype of hippocampal interneurons that express corticotropin-releasing hormone. Hippocampus 26: 41-53.   Abstract

Kelley MR, Deeb TZ, Brandon NJ, Dunlop J, Davies PA, Moss SJ. 2016. Compromising KCC2 transporter activity enhances the development of continuous seizure activity. Neuropharmacology. 108: 103-110. Abstract

Kilinc S, Savarino A, Coleman JH, Schwob JE, Lane RP. 2016. Lysine-specific demethylase-1 (LSD1) is compartmentalized at nuclear chromocenters in early post-mitotic cells of the olfactory sensory neuronal lineage. Mol Cell Neurosci. 74: 58-70. Abstract

Lee V, MacKenzie G, Hooper A, Maguire J. 2016. Reduced tonic inhibition in the dentate gyrus contributes to chronic stress-induced impairments in learning and memory. Hippocampus. 26: 1276-1290. Abstract

Modgil A, Parakala ML, Ackley MA, Doherty JJ, Moss SJ, Davies PA. 2016. Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism. Neuropharmacology 113(Pt A): 314-322.  Abstract

Moss BJ, Park L, Dahlberg CL, Juo P. 2016. The CaM kinase CMK-1 mediates a negative feedback mechanism coupling the C. elegans glutamate receptor GLR-1 with its own transcription. PLoS Genet. 12: e1006180. Abstract

Najjar M*, Saleh D*, Zelic M, Nogusa S, Shah A, Tai A, Finger JN, Polykratis A, Gough PJ, Bertin J, Whalen M, Pasparakis, Balachandran S, Kelliher M, Poltorak A, Degterev A. 2016. RIPK1 and RIPK3 kinases promote cell death-independent inflammation by TLR4-TRIF Immunity. 45: 46-59. * equal contribution. Abstract

Ng FS, Sengupta S, Huang Y, Yu AM, You S, Roberts MA, Iyer LK, Yang Y, Jackson FR. 2016. TRAP-seq profiling and RNAi-based genetic screens identify conserved glial genes required for adult Drosophila behavior. Front Mol Neurosci. 9: 146.  Abstract

Pirone A, Alexander J, Lau LA, Hampton D, Zayachkivsky A, Yee A, Yee A, Jacob MH, Dulla CG. 2016. APC conditional knock-out mouse is a model of infantile spasms with elevated neuronal β-catenin levels, neonatal spasms, and chronic seizures. Neurobiol Dis. 98: 149-157.  Abstract

Yeates EF, Tesco G 2016. The endosomal-associated deubiquitinating enzyme USP8 regulates BACE1 ubiquitination and degradation. J Biol Chem. 291:15753-15766. Abstract

2015

Canning P, Ruan Q, Schwerd T, Hrdinka M, Maki JL, Saleh D, Suebsuwong C, Ray S, Brennan PE, Cuny GD, Uhlig HH, Gyrd-Hansen M, Degterev A, Bullock AN. 2015. Inflammatory signaling by NOD-RIPK2 ss inhibited by clinically relevant type II kinase inhibitors. Chem Bio. pii: S1074-5521(15)00322-1. Abstract

Cantu D, Walker K, Andresen L, Taylor-Weiner A, Hampton D, Tesco G, Dulla CG. 2015. Traumatic brain injury increases cortical glutamate network activity by compromising GABAergic control. Cereb Cortex 25: 2306-2320. Abstract

Cook-Snyder DR, Jones A, Reijmers LG. 2015. A retrograde adeno-associated virus for collecting ribosome-bound mRNA from anatomically defined projection neurons. Front Mol Neurosci. 8: 56. Abstract

Garafalo SD, Luth ES, Moss BJ, Monteiro MI, Malkin E, Juo P. 2015. The AP2 clathrin adaptor protein complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans. Mol Biol Cell 26: 1887-1900. Abstract

Hanson E, Armbruster M, Cantu D, Andresen L, Taylor A, Danbolt NC, Dulla CG. 2015. Astrocytic glutamate uptake is slow and does not limit neuronal NMDA receptor activation in the neonatal neocortex. Glia 63: 1784-1796. Abstract

Hickman TT, Liberman MC, Jacob MH. 2015. Adenomatous polyposis coli protein deletion in efferent olivocochlear neurons perturbs afferent synaptic maturation and reduces the dynamic range of hearing. J Neurosci. 35: 9236-9245. Abstract

Jackson FR, Ng FS, Sengupta S, You S, Huang Y. 2015. Glial cell regulation of rhythmic behavior. Methods Enzymol. 552: 45-73. Abstract

Liu L, Peritore C, Ginsberg J, Shih J, Arun S, Donmez G. 2015. Protective role of SIRT5 against motor deficit and dopaminergic degeneration in MPTP-induced mice model of Parkinson's disease. Behav Brain Res. 281: 215-221. Abstract

McGehee AM, Moss BJ, Juo P. 2015. The DAF-7/TGF-β signaling pathway regulates abundance of the Caenorhabditis elegans glutamate receptor GLR-1. Mol Cell Neurosci. 67: 66-74. Abstract

Metallo C, Trimmer BA. 2015. Orientation-dependent changes in single motor neuron activity during adaptive soft-bodied locomotion. Brain Behav Evol. 85: 47-62. Abstract

Najjar M, Suebsuwong C, Ray SS, Thapa RJ, Maki JL, Nogusa S, Shah S, Saleh D, Gough PJ, Bertin J, Yuan J, Balachandran S, Cuny GD, Degterev A. 2015. Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1. Cell Rep. 10: 1850-1860. Abstract

Nakamura Y, Darnieder LM, Deeb TZ, Moss SJ. 2015. Regulation of GABAARs by phosphorylation. Adv Pharmacol. 72:97-146. Abstract

Ng SK, Higashimori H, Tolman M, Yang Y 2015. Suppression of adenosine 2a receptor (A2aR)-mediated adenosine signaling improves disease phenotypes in a mouse model of amyotrophic lateral sclerosis. Exp Neurol. 267: 115-122. Abstract

Saleh D, Degterev A. 2015. Emerging roles for RIPK1 and RIPK3 in pathogen-induced cell death and host immunity. Curr Topics Microbiol Immunol. Epub ahead of print.   Abstract

Schnittke N, Herrick DB, Lin B, Peterson J, Coleman JH, Packard AI, Jang W, Schwob JE. 2015. Transcription factor p63 controls the reserve status but not the stemness of horizontal basal cells in the olfactory epithelium. Proc Natl Acad Sci USA 112: E5068-E5077.  Abstract

Silayeva L, Deeb TZ, Hines RM, Kelley MR, Munoz MB, Lee HH, Brandon NJ, Dunlop J, Maguire J, Davies PA, Moss SJ. 2015. KCC2 activity is critical in limiting the onset and severity of status epilepticus. Proc Natl Acad Sci USA 112: 3523-3528. Abstract

Sivakumaran S, Cardarelli RA, Maguire J, Kelley MR, Silayeva L, Morrow DH, Mukherjee J, Moore YE, Mather RJ, Duggan ME, Brandon NJ, Dunlop J, Zicha S, Moss SJ, Deeb TZ. 2015. Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices in vitro and in vivo. J Neurosci. 35: 8291-8286. Abstract

Uzturk BG, Jin SX, Rubin B, Bartolome C, Feig LA. 2015. Ras-GRF1 regulates the HPA axis specifically in early-adolescent female mice. J Endocrinol. 227: 227-238.  Abstract

Wong LE, Gibson ME, Arnold HM, Pepinsky B, Frank E. 2015. Artemin promotes functional long-distance axonal regeneration to the brainstem after dorsal root crush. Proc Natl Acad Sci USA 112: 6170-6175. Abstract

2014

Abramian AM*, Comenencia-Ortiz E*, Modgil A, Vien TN, Nakamura Y, Moore YE, Maguire JL, Terunuma M, Davies PA, Moss SJ. 2014. Neurosteroids promote phosphorylation and membrane insertion of extrasynaptic GABAA receptors. Proc Natl Acad Scie USA 111: 7132-7137. (* equal contribution) Abstract

Ainsley JA, Drane L, Jacobs J, Kittelberger KA, Reijmers LG. 2014. Functionally diverse dendritic mRNAs rapidly associate with ribosomes following a novel experience. Nat Commun. 5: 4510. Abstract

Andresen L, Hampton D, Taylor A, Morel L, Yang Y, Maguire J, Dulla CG. 2014. Gabapentin attenuates hyperexcitability in the freeze-lesion model of developmental cortical malformation. Neurobiol Dis. 71: 305-316. Abstract

Clasadonte J, McIver SR, Schmitt LI, Halassa MM, Haydon PG. 2014. Chronic sleep restriction disrupts sleep homeostasis and behavioral sensitivity to alcohol by reducing the extracellular accumulation of adenosine. J Neurosci. 34: 1879-1891. Abstract

Comenencia-Ortiz E, Moss SJ, Davies PA. 2014. Phosphorylation of GABAA receptors influences receptor trafficking and neurosteroid actions. Psychopharmacology (Berl) 231: 3453-3465. Abstract

Cordeira JW, Felsted J, Teillon S, Daftary-Bussiere S, Wirth J, Sena-Esteves M, Rios M. 2014. Hypothalamic dysfunction of the calcium channel subunit underlies the overeating and obesity triggered by BDNF deficiency. J Neurosci. 34: 554-565. Abstract

Drane L, Ainsley JA, Mayford MR, Reijmers LG. 2014. A transgenic mouse line for collecting ribosome-bound mRNA using the tetracycline transactivator system. Front Mol Neurosci. 7: 82. Abstract

Kowalski JR, Dube H, Touroutine D, Goodwin PR, Carozza M, Didier Z, Francis MM, Juo P. 2014. The anaphase-promoting complex (APC) ubiquitin ligase regulates GABA transmission at the C. elegans neuromuscular junction. Mol Cell Neurosci. 58:62-75. Abstract

Lee V, Maguire J. 2014. The impact of tonic GABAA receptor-mediated inhibition on neuronal excitability varies across brain region and cell type. Front Neural Circuits 8: 3. Abstract

Lee V, Sarkar J, Maguire J. 2014. Loss of Gabrd in CRH neurons blunts the corticosterone response to stress and diminishes stress-related behaviors. Psychoneuroendocrinology 41: 75-88. Abstract

Mohn JL, Alexander J, Pirone A, Palka CD, Lee SY, Mebane L, Haydon PG, Jacob MH. 2014. New molecular insights into cognitive and autistic-like disabilities. Mol Psychiatry 19: 1053. Abstract

Mohn JL, Alexander J, Pirone A, Palka CD, Lee SY, Mebane L, Haydon PG, Jacob MH. 2014. Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities. Mol Psychiatry 19: 1133-1142. Abstract

Morel L, Higashimori H, Tolman M, Yang Y. 2014. VGluT1+ neuronal glutamatergic signaling regulates postnatal developmental maturation of cortical protoplasmic astroglia. J Neurosci. 34: 10950-10962. Abstract

O'Toole KK, Hooper A, Wakefield S, Maguire J. 2014. Seizure-induced disinhibition of the HPA axis increases seizure susceptibility. Epilepsy Res. 108: 29-43. Abstract

Shih J, Mason A, Liu L, Higashimori H, Donmez G. 2014. Loss of SIRT4 decreases GLT-1-dependent glutamate uptake and increases sensitivity to kainic acid. J Neurochem. 131: 573-581. Abstract