Howard Temin Lectureship to Honor Nobel Prize Recipient

Columbus, OH (September 30, 2009)John Coffin, Ph.D. John Coffin of Tufts University has been chosen to receive the Howard Temin Memorial Lectureship at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James).

The award will be presented Oct. 14 as part of a mini-symposium on “Comparative Models of Leukemia and Lymphoma” at OSUCCC-James.

The conference offers an internationally distinguished group of scientists, veterinarians, and physicians who will present the latest advances in comparative pre-clinical models of leukemia and lymphoma.

The symposium coincides with the opening of the new Center for Retrovirus Research laboratories, and serves as the opening day of the International Association for Comparative Research on Leukemia and Related Diseases (IARCLRD) Symposium XXIV, “Molecular Approaches to Leukemia in the 21st Century: Biology Outcome Prediction and Personalized Therapy” Oct.15-16 at OSUCCC-James.

Coffin is professor of molecular biology and microbiology at Tufts University School of Medicine and member of the molecular microbiology and genetics programs at the Sackler School of Gradate Biomedical Sciences at Tufts in Boston. He also is a special advisor to the director of the center for cancer research at the National Cancer Institute (NCI). He pioneered the use of genomic analysis to understand the biology of retroviruses, elucidating their genetic organization, mechanism of replication, recombination, and transduction. His work provided insight into retrovirus-host association, and he has played a major role in public policy issues on retroviral disease. Coffin received his doctorate from the University of Wisconsin in the laboratory of Howard Temin. In 1975, Coffin joined Tufts University in Boston, where he was later promoted to full professor, and in 1994 was the recipient of an American Cancer Society Professorship. In 1997, he was named director of the new HIV Drug Resistance Program at the NCI, a position he held until 2005, and he divides his time between Tufts University School of Medicine and the NCI.

Howard Temin, after whom the Lectureship is named, discovered reverse transcriptase in the 1970s at the University of Wisconsin-Madison. He won a Nobel Prize in Physiology or Medicine in 1975, along with David Baltimore and Renato Dulbecco, for describing how tumor viruses act on genes through reverse transcriptase. The Ohio State University Comprehensive Cancer Center- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is one of only 40 Comprehensive Cancer Centers in the United States designated by the National Cancer Institute. Ranked by U.S. News & World Report among the top 20 cancer hospitals in the nation, The James (www.jamesline.com) is the 180-bed adult patient-care component of the cancer program at The Ohio State University. The OSUCCC-James is one of only five centers in the country approved by the NCI to conduct both Phase I and Phase II clinical trials.

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