Recent Publications from the Yee & Paulson Lab

Research Publications Cell Biology Genetics Pharmacology


Pirone A, Alexander J, Lau LA, Hampton D, Zayachkivsky A, Yee A, Yee A, Jacob MH, Dulla CG. 2016. APC conditional knock-out mouse is a model of infantile spasms with elevated neuronal β-catenin levels, neonatal spasms, and chronic seizures. Neurobiol Dis. Epub ahead of print.  Abstract in PubMed

Mineva ND, Paulson KE, Naber SP, Yee AS, Sonenshein GE. 2013. Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells. PLoS One 8: e73464. books

Pan K, Chen Y, Roth M, Wang W, Wang S, Yee AS, Zhang X. 2013. HBP1-mediated transcriptional regulation of DNMT1 and its impact on cell senescence. Mol Cell Biol. 33: 887-903. Abstract in PubMed

Lee MF, Chan CY, Hung HC, Chou IT, Yee AS, Huang CY. 2013. N-acetylcysteine (NAC) inhibits cell growth by mediating the EGFR/Akt/HMG box-containing protein 1 (HBP1) signaling pathway in invasive oral cancer. Oral Oncol. 49: 129-135. Abstract in PubMed

Li H, Wang W, Liu X, Paulson KE, Yee AS, Zhang X. 2010. Transcriptional factor HBP1 targets P16(INK4A), upregulating its expression and consequently is involved in Ras-induced premature senescence. Oncogene 29: 5083-5094. Abstract in PubMed

Paulson KE, Rieger-Christ, KM, McDevitt MA, Kuperwasser C, Kim J, Zhang X, Hu M, Ruthazer R, Berasi SP, Huang CY, Paganelli RH, Giri D, Kaufman S, Dugan J, Blum J, Netto G, Huang Z, Wazer DE, Summerhayes IC, Yee AS. 2007. Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer. Cancer Res. 67: 6136-6145. Abstract in PubMed

Rieger-Christ KM, Hanley R, Lodowsky C, Bernier T, Vemulapalli P, Roth M, Kim J, Yee AS, Le SM, Marie PJ, Libertino JA, Summerhayes IC. 2007.  The green tea compound, (-)-epigallocatechin-3-gallate down-regulates N-cadherin and suppresses migration of bladder carcinoma cells. J Cell Biochem. 102: 377-388. Abstract in PubMed

Kim J, Zhang X, Rieger-Christ KM, Summerhayes IC, Wazer DE, Paulson KE, Yee AS. 2006 Suppression f Wnt signaling by the green tea compound EGCG nnd the HBP1 transcriptional repressor in breast cancer cells. J Biol Chem. 281: 10865-10875. Abstract in PubMed 

Zhang XW, Kim J, Ruthahzer R, Wazer DE, Paulson KE, Yee AS. 2006. The HBP1 transcriptional repressor participates in RAS-induced premature senescence. Mol Cell Biol. 26: 8252-8266. Abstract in PubMed

Rieger-Christ KM, Ng K, Hanley RS, Durrani O, Ma H, Yee AS, Libertino JA,  Summerhayes IC. 2005. Restoration of plakoglobin expression in bladder carcinoma cell lines suppresses cell migration and tumorigenic potential. Br J Cancer 92: 2153-2159. Abstract in PubMed

Wazer DE, Reiger-Christ K, McDevitt MA, Huang Z, Giri D, Kaufmann S, Kim J, Berasi SP, Summerhayes I, Paulson KE, Yee AS. 2005. Breast-cancer variants of the HBP1 transcriptional repressor: Association with invasive breast cancer. Int J Rad Oncol Biol Phys  63: S252.

Purviance J, Kim J, Stephan B, Yee AS, Paulson K, Wazer D. 2005. Loss of the HBP1 transcriptional repressor confers radiosensitivity to breast tumor cells. Int J Rad Oncol Biol Phys  63: S485-S486.

Sivak JM, West-Mays JA, Yee A, Williams T, Fini ME. 2004. Pax6 coordinates corneal re-epithelialization by controlling gelatinase B (MMP-9) expression through cooperative interactions with AP-2. Mol Cell Biol. 24: 245-257.  Abstract in PubMed

Berasi SP, Xiu M, Yee AS, Paulson KE. 2004. HBP1 repression of the p47 phox gene: Cell cycle regulation via the NADPH oxidase. Mol Cell Biol. 24: 3011-3024.  Abstract in PubMed

Yee AS, Paulson KE, McDevitt MA, Rieger-Christ KM, Summerhayes IK, Berasi SP, Kim J, Huang CY, Zhang X. 2004. Unlikely partners: the HBP1 transcriptional repressor and the p38 MAP kinase in G1 regulation and tumor suppression. Gene 336: 1-13. Abstract in PubMed

Xiu M, Sampson E, Huang CY, Davis RJ, Paulson KE, Yee AS. 2003. The transcriptional repressor HBP1 is a target of the p38 MAP kinase pathway. Mol Cell Biol. 23: 8890-8901. Abstract in PubMed

Souza SC, Palmer HJ, Kang YH, Yamamoto MT, Muliro KV, Paulson KE, Greenberg AS. 2003. TNF-α induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes. J Cell Biochem. 89: 1077-1086. books

Finlay GA, Hunter DS, Walker CL, Paulson KE, Fanburg BL. 2003. Regulation of PDGF production and ERK activation by estrogen is associated with TSC2 gene expression. Am J Physiol Cell Physiol. 285: C409-C418. books

Wu D, Marko M, Claycombe K, Paulson KE, Meydani SN. 2003. Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-κB activity. J Biol Chem. 278: 10982-10992. books

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December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research