Recent Publications from the Wojchowski Lab

Research Publications Cell Biology

 

Li P, Karaczyn AA, McGlauflin R, Favreau A, Jachimowicz E, Vary C, Xu K, Wojchowski DM, Sathyanarayana. 2017. Novel roles for podocalyxin in regulating stress myelopoiesis, Rap1a and neutrophil migration. Exp Haematol. Epub ahead of print. Abstract in PubMed

Dev A, Asch R, Jachimowicz E, Rainville N, Johnson A, Greenfest-Allen E, Wojchowski DM. 2017. Governing roles for Trib3 pseudokinase during stress erythropoiesis. Exp Hematol. Epub ahead of print. Abstract in PubMed

Verma R, Green JM, Schatz PJ, Wojchowski DM. 2016. A dimeric peptide with erythropoiesis stimulating activity uniquely affects erythropoietin receptor ligation and cell surface expression. Exp Hematol. Epub ahead of print. Abstract in PubMed

Rainville N, Jachimowicz E, Wojchowski DM. 2015. Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis. Expert Opin Ther Targets 30: 1-15. Abstract in PubMed

Verma R, Su S, McCrann DJ, Green JM, Leu K, Young PR, Schatz PJ, Silva JC, Stokes MP, Wojchowski DM. 2014. RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development. J Exp Med. 211: 1715-1722.   Abstract in PubMed

Wojchowski DM. 2014. Erythroid mRNA processing: a "splice of life". Blood 124: 474-475.   Abstract in PubMed

Li L, Byrne SM, Rainville N, Su S, Jachimowicz E, Aucher A, Davis DM, Ashton-Rickardt PG, Wojchowski DM. Brief report: serpin Spi2A as a novel modulator of hematopoietic progenitor cell formation. Stem Cells 32: 2550-2556.   Abstract in PubMed

Guay JA, Wojchowski DM, Fang J, Oxburgh L. 2014. Death associated protein kinase 2 is expressed in cortical interstitial cells of the mouse kidney. BMC Res Notes 7: 345.   Abstract in PubMed

Dev A, Byrne SM, Verma R, Ashton-Rickardt PG, Wojchowski DM. 2013. Erythropoietin-directed erythropoiesis depends on serpin inhibition of erythroblast lysosomal cathepsins. J Exp Med. 210: 225-232. Abstract in PubMed

Singh S, Dev A, Verma R, Pradeep A, Sathyanarayana P, Green JM, Narayanan A, Wojchowski DM. 2012. Defining an EPOR- regulated transcriptome for primary progenitors, including Tnfr-sf13c as a novel mediator of EPO- dependent erythroblast formation. PLoS One 7: e38530. Abstract in PubMed

Sathyanarayana P, Dev A, Pradeep A, Ufkin M, Licht JD, Wojchowski DM. 2012. Spry1 as a novel regulator of erythropoiesis, EPO/EPOR target, and suppressor of JAK2. Blood 119: 5522-5531. Abstract in PubMed

Green JM, Leu K, Worth A, Mortensen RB, Martinez DK, Schatz PJ, Wojchowski DM, Young PR. 2012. Peginesatide and erythropoietin stimulate similar erythropoietin receptor-mediated signal transduction and gene induction events. Exp Hematol. 40: 575-587. Abstract in PubMed

Singh S, Verma R, Pradeep A, Leu K, Mortensen RB, Young PR, Oyasu M, Schatz PJ, Green JM, Wojchowski DM. 2012. Dynamic ligand modulation of EPO receptor pools, and dysregulation by polycythemia-associated EPOR alleles. PLoS One 7: e29064. Abstract in PubMed

Wojchowski DM. 2010. Micro-mismanaging sickle cell stress. Blood 116: 4040-4042. Abstract in PubMed

Dev A, Fang J, Sathyanarayana P, Pradeep A, Emerson C, Wojchowski DM. 2010. During EPO or anemia challenge, erythroid progenitor cells transit through a selectively expandable proerythroblast pool. Blood 116: 5334-5346. Abstract in PubMed

Wojchowski DM, Sathyanarayana P, Dev A. 2010. Erythropoietin receptor response circuits. Curr Opin Hematol. 17: 169-176. Abstract in PubMed

Bai H, Gao Y, Arzigian M, Wojchowski DM, Wu WS, Wang ZZ. 2010. BMP4 regulates vascular progenitor development in human embryonic stem cells through a Smad-dependent pathway. J Cell Biochem. 109: 363-374. Abstract in PubMed

Sathyanarayana P, Houde E, Marshall D, Volk A, Makropoulos D, Emerson C, Pradeep A, Bugelski PJ, Wojchowski DM. 2010. CNTO 530 functions as a potent EPO mimetic via unique sustained effects on bone marrow proerythroblast pools. Blood 113: 4955-4962. Abstract in PubMed

Agosti V, Karur V, Sathyanarayana P, Besmer P, Wojchowski DM. 2009. A KIT juxtamembrane PY567 -directed pathway provides nonredundant signals for erythroid progenitor cell development and stress erythropoiesis. Exp Hematol. 37: 159-171. Abstract in PubMed

Bogacheva O, Bogachev O, Menon M, Dev A, Houde E, Valoret EI, Prosser HM, Creasy CL, Pickering SJ, Grau E, Rance K, Livi GP, Karur V, Erickson-Miller CL, Wojchowski DM. 2008. DYRK3 dual-specificity kinase attenuates erythropoiesis during anemia. J Biol Chem. 283: 36665-36675. Abstract in PubMed

Breggia AC, Wojchowski DM, Himmelfarb J. 2008. JAK2/Y343/STAT5 signaling axis is required for erythropoietin-mediated protection against ischemic injury in primary renal tubular epithelial cells. Am J Physiol Renal Physiol. 295: F1689-F1695. Abstract in PubMed

Blank U, Seto ML, Adams DC, Wojchowski DM, Karolak MJ, Oxburgh L. 2008. An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney. BMC Dev Biol. 8: 86. Abstract in PubMed

Hong L, Ramdas B, Chen J, Harris C, Wojchowski DM, Kapur R. 2008. KIT associated intracellular tyrosines play an essential role in EpoR co-signaling. Cell Signal 20: 1513-1520. Abstract in PubMed

Fang J, Menon M, Zhang D, Torbett B, Oxburgh L, Tschan M, Houde E, Wojchowski DM. 2008. Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2. Blood 112: 886-890. Abstract in PubMed

Sathyanarayana P, Dev A, Fang J, Houde E, Bogacheva O, Bogachev O, Menon M, Browne S, Pradeep A, Emerson C, Wojchowski DM. 2008. EPO receptor circuits for primary erythroblast survival. Blood 111: 5390-5399. Abstract in PubMed

Fang J, Menon M, Kapelle W, Bogacheva O, Bogachev O, Houde E, Browne S, Sathyanarayana P, Wojchowski DM. 2007. EPO modulation of cell-cycle regulatory genes, and cell division, in primary bone marrow erythroblasts. Blood 110: 2361-2370. Abstract in PubMed

Sathyanarayana P, Menon MP, Bogacheva O, Bogachev O, Niss K, Kapelle WS, Houde E, Fang J, Wojchowski DM. 2007. Erythropoietin modulation of podocalyxin and a proposed erythroblast niche. Blood 110: 509-518. Abstract in PubMed

Karur VG, Lowell CA, Besmer P, Agosti V, Wojchowski DM. 2006. Lyn kinase promotes erythroblast expansion and late-stage development. Blood 108: 1524-1532. Abstract in PubMed

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