Recent Publications from the Vary Lab

Research Publications Cell Biology


Li P, Karaczyn AA, McGlauflin R, Favreau A, Jachimowicz E, Vary C, Xu K, Wojchowski DM, Sathyanarayana. 2017. Novel roles for podocalyxin in regulating stress myelopoiesis, Rap1a and neutrophil migration. Exp Haematol. Epub ahead of print. Abstract in PubMed

Uygur B, Abramo K, Leikina E, Vary C, Liaw L, Wu WS. 2015. SLUG is a direct transcriptional repressor of PTEN tumor suppressor. Prostate 75: 907-916. books

Rostama B, Peterson SM, Vary CPH, Liaw L. 2014. Notch signal integration in the vasculature during remodeling.  J Vasc Pharmacol. 63: 97-114.books

Contois LW, Akalu A, Caron JM, Tweedie E, Cretu A, Henderson T, Liaw L, Friesel R, Vary C, Brooks PC. 2015. Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo. Angiogenesis 18: 31-46. books

Breen MJ, Moran DM, Liu W, Huang X, Vary CP, Bergan RC. 2013. Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors. PLoS One 8: e72407. books

Duarte CW, Murray K, Lucas FL, Fairfield K, Miller H, Brooks P, Vary CP. 2013. Improved survival outcomes in cancer patients with hereditary hemorrhagic telangiectasia. Cancer Epidemiol Biomarkers Prev. 23: 117-125.  books

Favreau AJ, Vary CP, Brooks PC, Sathyanarayana P. Cryptic collagen IV promotes cell migration and adhesion in myeloid leukemia. Cancer Med. 3: 265-272.  books

Gong Y, Yang X, He Q, Gower L, Prudovsky I, Vary CP, Brooks PC, Friesel RE. 2013. Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src. Angiogenesis 16: 861-875.  books

Young K, Conley B, Romero D, Tweedie E, O'Neill C, Pinz I, Brogan L, Lindner V, Liaw L, Vary CP. 2012. BMP9 regulates endoglin-dependent chemokine responses in endothelial cells. Blood 120: 4263-4273. books

Contois LW, Nugent DP, Caron JM, Cretu A, Tweedie E, Akalu A, Liebes L, Friesel R, Rosen C, Vary C, Brooks PC. 2012. Insulin-like growth factor binding protein-4 differentially inhibits growth factor-induced angiogenesis. J Biol Chem. 287: 1779-1789. Abstract in PubMed

Tang Y, Yang X, Friesel RE, Vary CP, Liaw L. 2011. Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells. J Vasc Res. 48: 485-494. books

Mathers A, Smith RP, Cahill B, Lubelczyk C, Elias SP, Lacombe E, Morris SR, Vary CP, Parent CE, Rand PW.  2011. Strain diversity of Borrelia burgdorferi in ticks dispersed in North America by migratory birds. J Vector Ecol. 36: 24-29. Abstract in PubMed

Romero D, O'Neill CF, Terzic A, Contois L, Young K, Conley BA, Bergan RC, Brooks PC, Vary CP. 2011. Endoglin regulates cancer-stromal cell interactions in prostate tumors. Cancer Res. 71: 3482-3493.  Abstract in PubMed

Venkatesh D, Fredette N, Rostama B, Tang Y, Vary CP, Liaw L, Urs S. 2011. RhoA-Mediated Signaling in Notch-Induced Senescence-Like Growth Arrest and Endothelial Barrier Dysfunction. Arterioscler Thromb Vasc Biol. 31: 876-882. Abstract in PubMed

Karaczyn A, Bani-Yaghoub M, Tremblay R, Kubu C, Cowling R, Adams TL, Prudovsky I, Spicer D, Friesel R, Vary C, Verdi JM. 2010. Two novel human NUMB isoforms provide a potential link between development and cancer. Neural Dev. 5: 31. Abstract in PubMed

Lakshman M, Huang X, Ananthanarayanan V, Jovanovic B, Liu Y, Craft CS, Romero D, Vary CP, Bergan RC. 2010. Endoglin suppresses human prostate cancer metastasis. Clin Exp Metastasis. 28: 39-53. Abstract in PubMed

Santibanez JF, Pérez-Gómez E, Fernandez-L A, Garrido-Martin EM, Carnero A, Malumbres M, Vary CP, Quintanilla M, Bernabéu C. 2010. The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras. Carcinogenesis 31: 2145-2154. Abstract in PubMed

Garrido-Martin EM, Blanco FJ, Fernandez-L A, Langa C, Vary CP, Lee UE, Friedman SL, Botella LM, Bernabeu C. 2010. Characterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1. BMC Mol Biol. 11: 51. Abstract in PubMed

Liu J, Uygur B, Zhang Z, Shao L, Romero D, Vary C, Ding Q, Wu WS. 2010. Slug inhibits proliferation of human prostate cancer cells via downregulation of cyclin D1 expression. Prostate 70: 1768-1777. Abstract in PubMed

Tang Y, Urs S, Boucher J, Bernaiche T, Venkatesh D, Spicer DB, Vary CP, Liaw L. 2010. Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation. J Biol Chem. 285: 17556-17563. Abstract in PubMed

Romero D, Terzic A, Conley BA, Craft CS, Jovanovic B, Bergan RC, Vary CP. 2010. Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration. Carcinogenesis 31: 359-366. Abstract in PubMed

Mouta-Bellum C, Kirov A, Miceli-Libby L, Mancini ML, Petrova TV, Liaw L, Prudovsky I, Thorpe PE, Miura N, Cantley LC, Alitalo K, Fruman DA, Vary CP. 2009. Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha. Dev Dyn. 238: 2670-2679. Abstract in PubMed

Mancini ML, Terzic A, Conley BA, Oxburgh LH, Nicola T, Vary CP. 2009. Endoglin plays distinct roles in vascular smooth muscle cell recruitment and regulation of arteriovenous identity during angiogenesis. Dev Dyn. 238: 2479-2493. Abstract in PubMed

Nikopoulos GN, Martins JF, Adams TL, Karaczyn A, Adams D, Vary C, Oxburgh L, Verdi JM. 2009. NRAGE: a potential rheostat during branching morphogenesis. Mech Dev. 126: 337-349. Abstract in PubMed

Romero D, Iglesias M, Vary CP, Quintanilla M. 2008. Functional blockade of Smad4 leads to a decrease in beta-catenin levels and signaling activity in human pancreatic carcinoma cells. Carcinogenesis 29: 1070-1076. Abstract in PubMed

Bernabeu C, Conley BA, Vary CP. 2007. Novel biochemical pathways of endoglin in vascular cell physiology. J Cell Biochem. 102: 1375-1388. Abstract in PubMed

Craft CS, Xu L, Romero D, Vary CP, Bergan RC. 2007. Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells. Mol Pharmacol. 73: 235-242. Abstract in PubMed

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