Recent Publications from the Soto & Sonnenschein Lab

Research Publications Cell Biology Genetics

 

Soto AM, Schaeberle C, Maier MS, Sonnenschein C, Maffini MV. 2017. Evidence of absence: Estrogenicity assessment of a new food-contact coating and the bisphenol used in its synthesis. Environ Sci Technol. 51: 1718-1726.  books

Speroni L, Voutilainen M, Mikkola ML, Klager SA, Schaeberle CM, Sonnenschein C, Soto AM. 2017. New insights into fetal mammary gland morphogenesis: differential effects of natural and environmental estrogens. Sci Rep. 7: 40806. books

Soto AM, Longo G, Noble D. 2016. Preface to "From the century of the genome to the century of the organism: New theoretical approaches". Prog Biophys Mol Biol. 122: 1-3.  books

Montévil M, Speroni L, Sonnenschein C, Soto AM. 2016. Modeling mammary organogenesis from biological first principles: Cells and their physical constraints. Prog Biophys Mol Biol. Epub ahead of print. books

Sonnenschein C, Soto A. 2016. Carcinogenesis explained within the context of a theory of organisms. Prog Biophys Mol Biol. Epub ahead of print. books

Soto AM, Longo G, Miquel PA, Montevil M, Mossio M, Perret N, Pocheville A, Sonnenschein C. 2016. Toward a theory of organisms: Three founding principles in search of a useful integration. Prog Biophys Mol Biol. Epub ahead of print. books

Schug TT, Johnson AF, Birnbaum LS, Colborn T, Guillette LJ Jr, Crews DP, Collins T, Soto AM, Vom Saal FS, McLachlan JA, Sonnenschein C, Heindel JJ. 2016. Minireview: Endocrine disruptors: Past lessons and future directions. Mol Endocrinol. 30: 833-847. books

Soto AM, Longo G, Montévil M, Sonnenschein C. 2016. The biological default state of cell proliferation with variation and motility, a fundamental principle for a theory of organisms. Prog Biophys Mol Biol. Epub ahead of print. books

Longo G, Soto AM. 2016. Why do we need theories? Prog Biophys Mol Biol. Epub ahead of print. books

Zalko D, Soto AM, Canlet C, Tremblay-Franco M, Jourdan F, Cabaton NJ. 2016. Bisphenol A exposure disrupts neurotransmitters through modulation of transaminase activity in the brain of rodents. Endocrinology 157: 1736-1739. books

Paulose T, Montévil M, Speroni L, Cerruti F, Sonnenschein C, Soto AM. 2016. SAMA: A method for 3D morphological analysis. PLoS One 11: e0153022. books

Speroni L, Sweeney MF, Sonnenschein C, Soto AM. 2016. A hormone-responsive 3D culture model of the human mammary gland epithelium. J Vis Exp. Feb 7 (108). books

Sweeney MF, Hasan N, Soto AM, Sonnenschein C. 2016. Environmental endocrine disruptors: Effects on the human male reproductive system. Rev Endocr Metab Disord. 16: 341-357. books

Sonnenschein C, Soto AM. 2015. Cancer metastases: So close and so far. J Natl Cancer Inst. 107.   books

Soto AM, Sonnenschein C. 2015. Endocrine disruptors: DDT, endocrine disruption and breast cancer. Nat Rev Endocrinol. 11: 507-508.   books

Liu Z, Quinn KP, Speroni L, Arendt L, Kuperwasser C, Sonnenschein C, Soto AM, Georgakoudi I. 2015. Rapid three-dimensional quantification of voxel-wise collagen fiber orientation. Biomed Opt Express 6: 2294-2310.  books

Sonnenschein C, Davis B, Soto AM. 2014. A novel pathogenic classification of cancers. Cell Cancer Int. 14: 113. books

Paulose T, Speroni L, Sonnenschein C, Soto AM. 2014. Estrogens in the wrong place at the wrong time: Fetal BPA exposure and mammary cancer. Reprod Toxicol. 54: 58-65. books

Dhimolea E, Wadia PR, Murray TJ, Settles ML, Treitman JD, Sonnenschein C, Shioda T, Soto AM. 2014. Prenatal dxposure to BPA alters the epigenome of the rat mammary gland and increases the propensity to neoplastic development. PLoS One 9: e99800. books

Sonnenschein C, Soto AM. 2014. Cancer and the elusive cancer genes. Med Sci (Paris) 30: 688-692. books

Barnes C, Speroni L, Quinn KP, Montevil M, Saetzler K, Bode-Animashaun G, McKerr G, Georgakoudi I, Downes CS, Sonnenschein C, Howard CV, Soto AM. 2014. From single cells to tissues: Interactions between the matrix and human breast cells in real time. PLoS One 9: e93325. books

Sonnenschein C, Soto AM. Rangarajan A, Kulkarni P. 2014. Competing views on cancer. J Biosci. 39: 1-22.   books

Soto AM, Sonnenschein C 2014. One hundred years of somatic mutation theory of carcinogenesis: Is it time to switch? Bioessays 36:118-120. books

Speroni L, Whitt GS, Xylas J, Quinn KP, Jondeau-Cabaton A, Barnes C, Georgakoudi I, Sonnenschein C, Soto AM. 2014. Hormonal regulation of epithelial organization in a three-dimensional breast tissue culture model. Tissue Eng Part C Methods 20: 42-51. books

Bergman Å, Andersson AM, Becher G, van den Berg M, Blumberg B, Bjerregaard P, Bornehag CG, Bornman R, Brandt I, Brian JV, Casey SC, Fowler PA, Frouin H, Giudice LC, Iguchi T, Hass U, Jobling S, Juul A, Kidd KA, Kortenkamp A, Lind M, Martin OV, Muir D, Ochieng R, Olea N, Norrgren L, Ropstad E, Ross PS, Rudén C, Scheringer M, Skakkebaek NE, Söder O, Sonnenschein C, Soto A, Swan S, Toppari J, Tyler CR, Vandenberg LN, Vinggaard AM, Wiberg K, Zoeller RT. 2013. Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors. Environ Health 12: 69. books

Cabaton NJ, Canlet C, Wadia PR, Tremblay-Franco M, Gautier R, Molina J, Sonnenschein C, Cravedi JP, Rubin BS, Soto AM, Zalko D. 2013. Effects of low doses of bisphenol A on the metabolome of perinatally exposed CD-1 mice. Environ Health Perspect. 121: 586-593. books

Acevedo N, Davis B, Schaeberle CM, Sonnenschein C, Soto AM. 2013. Perinatally administered bisphenol A acts as a mammary gland carcinogen in rats. Environ Health Perspect. 121: 1040-1046. books

Soto AM, Sonnenschein C. 2013. Paradoxes in Carcinogenesis: There Is Light at the End of That Tunnel! Disrupt Sci Technol. 1: 154-156. books

Sonnenschein C, Soto AM. 2013. Cancer genes: The vestigal remains of a fallen theory. In: Genetic Explanations, Sense and Nonsense. S Krimsky, ed. , Harvard University Press, Cambridge, MA., pp81-93.

Sonnenschein C, Lee D, Nguyen J, Soto AM. 2013. Unanticipated trends stemming from the history of cell culture: Vitalism in 2012? In: Vitalism and the Scientific Image in Post-enlightenment Life Science, 1800-2010, S Normandin, C Wolfe, eds, Springer, pp 292-310.

Wadia PR, Cabaton NJ, Borrero MD, Rubin BS, Sonnenschein C, Shioda T, Soto AM. 2013. Low-Dose BPA exposure alters the mesenchymal and epithelial transcriptomes of the mouse fetal mammary gland. PLoS One 8: e63902. books

Soto AM, Brisken C, Schaeberle C, Sonnenschein C. 2013. Does cancer start in the womb? Altered mammary gland development and predisposition to breast cancer due to in utero exposure to endocrine disruptors. J Mamm Gland Biol Neoplasia 18: 199-208. books

Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR Jr, Lee DH, Myers JP, Shioda T, Soto AM, Vom Saal FS, Welshons WV, Zoeller RT. 2013. Regulatory decisions on endocrine disrupting chemicals should be based on the principles of endocrinology. Reprod Toxicol. 38: 1-15. books

Vandenberg LN, Schaeberle CM, Rubin BS, Sonnenschein C, Soto AM. 2013. The male mammary gland: a target for the xenoestrogen bisphenol A. Reprod Toxicol. 37: 15-23. books

Longo G, Miquel PA, Sonnenschein C, Soto AM. 2012. Is information a proper observable for biological organization? Prog Biophys Mol Biol. 109: 108-114. books

Zoeller RT, Brown TR, Doan LL, Gore AC, Skakkebaek NE, Soto AM, Woodruff TJ, Vom Saal FS. 2012. Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society. Endocrinology 153: 4097-4110. books

Dhimolea E, Soto AM, Sonnenschein C. 2012. Breast epithelial tissue morphology is affected in 3D cultures by species-specific collagen-based extracellular matrix. 2012. Breast epithelial tissue morphology is affected in 3D cultures by species-specific collagen-based extracellular matrix. J Biomed Mater Res A. 100: 2905-2912. books

Tharp AP, Maffini MV, Hunt PA, VandeVoort CA, Sonnenschein C, Soto AM. 2012. Bisphenol A alters the development of the rhesus monkey mammary gland. Proc Natl Acad Sci USA 109: 8190-8195. books

Soto AM, Sonnenschein C. 2012. Is systems biology a promising approach to resolve controversies in cancer research? Cancer Cell Int. 12: 12. books

Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR Jr, Lee DH, Shioda T, Soto AM, vom Saal FS, Welshons WV, Zoeller RT, Myers JP. 2012. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endcrin Rev. 33: 378-455. books

Krause S, Jondeau-Cabaton A, Dhimolea E, Soto AM, Sonnenschein C, Maffini MV. 2012. Dual regulation of breast tubulogenesis using extracellular matrix composition and stromal cells. Tissue Eng Part A. 18: 520-532. books

Soto AM, Sonnenschein C, Maini PK, Noble D. 2011. Systems biology and cancer. Prog Biophys Mol Biol. 106: 337-339. books

Pageau SC, Sazonova OV, Wong JY, Soto AM, Sonnenschein C. 2011. The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture. Biomaterials 32: 7169-7180. books

Sonnenschein C, Soto AM. 2011. Why systems biology and cancer? Semin Cancer Biol. 21: 147-149. books

Saetzler K, Sonnenschein C, Soto AM. 2011. Systems biology beyond networks: generating order from disorder through self-organization. Semin Cancer Biol. 21: 165-174. books

Bizzarri M, Giuliani A, Cucina A, D'Anselmi F, Soto AM, Sonnenschein C. 2011.Fractal analysis in a systems biology approach to cancer. Semin Cancer Biol. 21: 175-182. books

Sonnenschein C, Soto AM. 2011. The death of the cancer cell. Cancer Res. 71: 4334-4337. books

Soto AM, Sonnenschein C. 2011. The tissue organization field theory of cancer: a testable replacement for the somatic mutation theory. Bioessays. 33: 332-340. books

Cabaton NJ, Wadia PR, Rubin BS, Zalko D, Schaeberle CM, Askenase MH, Gadbois JL, Tharp AP, Whitt GS, Sonnenschein C, Soto AM. 2011. Perinatal exposure to environmentally relevant levels of bisphenol A decreases fertility and fecundity in CD-1 mice. Environ Health Perspect. 119: 547-552. books

Sonnenschein C, Soto AM. 1999. The Society of Cells: Cancer and Control of Cell Proliferation. New York, Springer Verlag.

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