Recent Publications from the Schwob Lab

Research Publications Cell Biology Genetics Neuroscience


Lin B, Coleman JH, Peterson JN, Zunitch MJ, Jang W, Herrick DB, Schwob JE. 2017. Injury induces endogenous reprogramming and dedifferentiation of neuronal progenitors to multipotency. Cell Stem Cell Epub ahead of print. books

Peterson JN, Lin B, Shin J, Phelan PJ, Tsichlis P, Schwob JE, Bullock PA. 2017. The Replication of JCV DNA in the G144 oligodendrocyte cell line is dependent upon Akt. J Virol. Epub ahead of print.  books

Herrick DB, Lin B, Peterson J, Schnittke N, Schwob JE. 2017. Notch1 maintains dormancy of olfactory horizontal basal cells, a reserve neural stem cell. Proc Natl Acad Sci USA Epub ahead of print. books

Coleman JH, Lin B, Schwob JE. 2017. Dissecting LSD1-dependent neuronal maturation in the olfactory epithelium  pub ahead of print. Comp Neurol. Epub ahead of print. books

Packard AI, Lin B, Schwob JE. 2016. Sox2 and Pax6 play counteracting roles in regulating neurogenesis within the murine olfactory epithelium. PLoS One 11: e0155167. books

Kilinc S, Savarino A, Coleman JH, Schwob JE, Lane RP. 2016. Lysine-specific demethylase-1 (LSD1) is compartmentalized at nuclear chromocenters in early post-mitotic cells of the olfactory sensory neuronal lineage. Mol Cell Neurosci. 74: 58-70. books

Gilbert MA, Lin B, Peterson J, Jang W, Schwob JE. 2015. Neuregulin1 and ErbB expression in the uninjured and regenerating olfactory mucosa. Gene Exp Patterns 19: 108-119. books

Joiner AM, Green WW, McIntyre JC, Allen BL, Schwob JE, Martens JR. 2015. Primary cilia on horizontal basal cells regulate regeneration of the olfactory epithelium. J Neurosci. 35: 13761-13772.   books

Schnittke N, Herrick DB, Lin B, Peterson J, Coleman JH, Packard AI, Jang W, Schwob JE. 2015. Transcription factor p63 controls the reserve status but not the stemness of horizontal basal cells in the olfactory epithelium. Proc Natl Acad Sci USA 112: E5068-E5077.  books

Mori M, Mahoney JE, Stupnikov MR, Paez-Cortez JR, Szymaniak AD, Varelas X, Herrick DB, Schwob J, Zhang H, Cardoso WV 2015. Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors. Development 142: 258-267. books

Holbrook EH, Iwema CL, Peluso CE, Schwob JE. 2014. The regeneration of P2 olfactory sensory neurons Is selectively impaired following methyl bromide lesion. Chem Senses 39: 601-616. books

Cheung MC, Jang W, Schwob JE, Wachowiak M. 2014. Functional recovery of odor representations in regenerated sensory inputs to the olfactory bulb. Front Neural Circuits 7: 207. Abstract in PubMed

Jang W, Chen X, Flis D, Harris M, Schwob JE. 2014. Label-retaining, quiescent globose basal cells are found in the olfactory epithelium. J Comp Neurol. 522: Spc1. books

Cheung MC, Jang W, Schwob JE, Wachowiak M. 2014. Functional recovery of odor representations in regenerated sensory inputs to the olfactory bulb. Front Neural Circuits. 7: 207. books

Jang W, Chen X, Flis D, Harris M, Schwob JE. 2013. Label-retaining, quiescent globose basal cells are found in the olfactory epithelium. J Comp Neurol. 522: 731-749. books

Xie F, Fang C, Schnittke N, Schwob JE, Ding X. 2013. Mechanisms of permanent loss of olfactory receptor neurons induced by the herbicide 2,6-dichlorobenzonitrile: Effects on stem cells and noninvolvement of acute induction of the inflammatory cytokine IL-6. Toxicol Appl Pharmacol. 272: 598-607. books

Krolewski RC, Packard A, Schwob JE. 2013. Global expression profiling of globose basal cells and neurogenic progression within the olfactory epithelium. J Comp Neurol. 521: 833-859. books

Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE. 2012. Ascl1 (mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One 7: e51737. books

Peluso CE, Jang W, Dräger UC, Schwob JE. 2012. Differential expression of components of the retinoic acid signaling pathway in the adult mouse olfactory epithelium. J Comp Neurol. 520: 3707-3726. books

Packard A, Giel-Moloney M, Leiter A, Schwob JE. 2011. Progenitor cell capacity of NeuroD1-expressing globose basal cells in the mouse olfactory epithelium. J Comp Neurol. 519: 3580-3596. books

Holbrook EH, Wu E, Curry WT, Lin DT, Schwob JE. 2011. Immunohistochemical characterization of human olfactory tissue. Laryngoscope. 121: 1687-1701. books

Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE. 2011. DeltaNp63 regulates stem cell dynamics in the mammalian olfactory epithelium. J Neurosci. 34: 8748-8759. books

Wang YZ, Yamagami T, Gan Q, Wang Y, Zhao T, Hamad S, Lott P, Schnittke N, Schwob JE, Zhou CJ. 2011. Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration. J Cell Sci. 124: 1553-1563. books

Krolewski RC, Jang W, Schwob JE. 2011. The generation of olfactory epithelial neurospheres in vitro predicts engraftment capacity following transplantation in vivo. Exp Neurol. 229: 308-323. books

Thompson KJ, Molina RM, Donaghey T, Savaliya S, Schwob JE, Brain JD. 2011. Manganese uptake and distribution in the brain after methyl bromide-induced lesions in the olfactory epithelia. Toxicol Sci. 120: 163-172. books

Guo Z, Packard A, Krolewski RC, Harris MT, Manglapus GL, Schwob JE. 2010. J Comp Neurol. 51: 4395-4418. books

Bakos SR, Schwob JE, Costanzo RM. 2010. Matrix metalloproteinase-9 and -2 expression in the olfactory bulb following methyl bromide gas exposure. Chem Senses 35: 655-661. books

Christie SB, Akins MR, Schwob JE, Fallon JR. 2009. The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits. J Neurosci. 29: 1514-1524. books

Jang W, Lambropoulos J, Woo JK, Peluso CE, Schwob JE. 2008. Maintaining epitheliopoietic potency when culturing olfactory progenitors. Exp Neurol. 214: 25-36. books

Jang W, Kim KP, Schwob JE. 2007. Nonintegrin laminin receptor precursor protein is expressed on olfactory stem and progenitor cells. J Comp Neurol 502: 367-381. books

Thompson K, Molina RM, Donaghey T, Schwob JE, Brain JD, Wessling-Resnick M. 2007. Olfactory uptake of manganese requires DMT1 and is enhanced by anemia.  FASEB J. 21: 223-230. books

Youngentob SL, Schwob JE. 2006. Odorant identification and quality perception following methyl bromide-induced lesions of the olfactory epithelium. Behav Neurosci. 120: 1346-1355. books

Holbrook EH, Leopold DA, Schwob JE. 2005. Abnormalities of axon growth in human olfactory mucosa. Laryngoscope 115: 2144-2154. books

Schwob JE. 2005. Restoring olfaction: A view from the olfactory epithelium. Chem Senses 30 (Suppl 1): i131-i132. books

Manglapus GL, Youngentob SL, Schwob JE. 2004. Expression patterns of basic helix-loop-helix transcription factors define subsets of olfactory progenitor cells. J Comp Neurol. 479: 216-233. books

Hamlin JA, Fang H, Schwob JE. 2004. Differential expression of the mammalian homologue of fasciclin II during olfactory development in vivo and in vitro. J Comp Neurol. 474: 438-452. books

McMillan Carr V, Ring G, Youngentob SL, Schwob JE, Farbman AI. 2004. Altered epithelial density and expansion of bulbar projections of a discrete HSP70 immunoreactive subpopulation of rat olfactory receptor neurons in reconstituting olfactory epithelium following exposure to methyl bromide. J Comp Neurol. 469: 475-493. books

Chen X, Fang H, Schwob JE. 2004. Multipotency of purified, transplanted globose basal cells in olfactory epithelium. J Comp Neurol. 469: 457-474. books

Iwema CL, Fang H, Kurtz DB, Youngentob SL, Schwob JE. 2004. Odorant receptor expression patterns are restored in lesion-recovered rat olfactory epithelium. J Neurosci. 24: 356-369. books

Jang W, Youngentob SL, Schwob JE. 2003. Globose basal cells are required for reconstitution of olfactory epithelium after methyl bromide lesion. J Comp Neurol. 460: 123-140. books

Iwema CL, Schwob JE. 2003.  Odorant receptor expression as a function of neuronal maturity in the adult rodent olfactory system. J Comp Neurol. 459: 209-222. books

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