Recent Publications from the Prudovsky Lab

Research Publications Cell Biology


Jayanthi S, Kathir KM, Rajalingam D, Furr M, Daily A, Thurman R, Rutherford L, Chandrashekar R, Adams P, Prudovsky I, Kumar TK. 2014. Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factor. Biochim Biophys Acta. 1844: 2155-2163.  books

Wang T, Green LA, Gupta SK, Kim C, Wang L, Almodovar S, Flores SC, Prudovsky IA, Jolicoeur P, Liu Z, Clauss M. Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction. PLoS One 9: e91063.  books

Prudovsky I. 2014. Nonclassically secreted regulators of angiogenesis. Angiol Open Access 1: 1000101.  books

Poole A, Knowland N, Cooper E, Cole R, Wang H, Booth L, Kacer D, Tarantini F, Friesel R, Prudovsky I. 2014. Transitory FGF treatment results in the long-lasting suppression of the proliferative response to repeated FGF stimulation. J Cell Biochem. 115: 874-888.  books

Gong Y, Yang X, He Q, Gower L, Prudovsky I, Vary CP, Brooks PC, Friesel RE. 2013. Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src. Angiogenesis 16: 861-875.  books

Danza G, Di Serio C, Ambrosio MR, Sturli N, Lonetto G, Rosati F, Rocca BJ, Ventimiglia G, Del Vecchio MT, Prudovsky I, Marchionni N, Tarantini F. 2013. Notch3 is activated by chronic hypoxia and contributes to the progression of human prostate cancer. Int J Cancer 133: 2577-2586. books

Sterling SM, Allgeyer ES, Fick J, Prudovsky I, Mason MD, Neivandt DJ. 2013. Phospholipid diffusion coefficients of cushioned model membranes determined via z-scan fluorescence correlation spectroscopy. Langmuir 29: 7966-7944. books

Prudovsky I, Kumar TK, Sterling S, Neivandt D. 2013. Protein-phospholipid interactions in nonclassical protein secretion: problem and methods of study. Int J Mol Sci. 14: 3734-3772. books

Lopez-Castejon G, Luheshi NM, Compan V, High S, Whitehead RC, Flitsch SL, Kirov A, Prudovsky I, Swanton E, Brough D. 2013. Deubiquitinases regulate the activity of caspase-1 and IL-1β secretion via assembly of the inflammasome. J Biol Chem. 288: 2721-2733. books

Meng H, Zhang X, Yu G, Lee SJ, Chen YE, Prudovsky I, Wang MM. 2012. Biochemical characterization and cellular effects of CADASIL mutants of NOTCH3. PLoS One 7: e44964. books

Prudovsky I, Vary CP, Markaki Y, Olins AL, Olins DE. 2012. Phosphatidylserine colocalizes with epichromatin in interphase nuclei and mitotic chromosomes. Nucleus 3: 200-210. books

Danza G, Di Serio C, Rosati F, Lonetto G, Sturli N, Kacer D, Pennella A, Ventimiglia G, Barucci R, Piscazzi A, Prudovsky I, Landriscina M, Marchionni N, Tarantini F. 2012. Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells. Mol Cancer Res. 10: 230-238. books

Kirov A, Al-Hashimi H, Solomon P, Mazur C, Thorpe PE, Sims PJ, Tarantini F, Kumar TK, Prudovsky I. 2012. Phosphatidylserine externalization and membrane blebbing are involved in the nonclassical export of FGF1. J Cell Biochem. 113: 956-966. books

Kirov A, Duarte M, Guay J, Karolak M, Yan C, Oxburgh L, Prudovsky I. 2012. Transgenic expression of nonclassically secreted FGF suppresses kidney repair. PLoS One 7: e36485. books

Kacer D, McIntire C, Kirov A, Kany E, Roth J, Liaw L, Small D, Friesel R, Basilico C, Tarantini F, Verdi J, Prudovsky I. 2011. Regulation of nonclassical fgf1 release and fgf-dependent cell transformation by CBF1-mediated notch signaling. J Cell Physiol. 226: 3064-3075. books

Karaczyn A, Bani-Yaghoub M, Tremblay R, Kubu C, Cowling R, Adams TL, Prudovsky I, Spicer D, Friesel R, Vary C, Verdi JM. 2010. Two novel human NUMB isoforms provide a potential link between development and cancer. Neural Dev. 5: 31. books

Massi D, Landriscina M, Piscazzi A, Cosci E, Kirov A, Paglierani M, Di Serio C, Mourmouras V, Fumagalli S, Biagioli M, Prudovsky I, Miracco C, Santucci M, Marchionni N, Tarantini F. 2010. S100A13 is a new angiogenic marker in human melanoma. Mod Pathol. 23: 804-813. books

NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I-relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1). Biochim Biophys Acta 1798: 297-302. books

Mouta-Bellum C, Kirov A, Miceli-Libby L, Mancini ML, Petrova TV, Liaw L, Prudovsky I, Thorpe PE, Miura N, Cantley LC, Alitalo K, Fruman DA, Vary CP. 2009. Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha. Dev Dyn. 238: 2670-2679. books

Graziani I, Doyle A, Sterling S, Kirov A, Tarantini F, Landriscina M, Kumar TK, Neivandt D, Prudovsky I. 2009. Protein folding does not prevent the nonclassical export of FGF1 and S100A13. Biochem Biophys Res Commun. 381: 350-354. books

Duarte M, Kolev V, Kacer D, Mouta-Bellum C, Soldi R, Graziani I, Kirov A, Friesel R, Liaw L, Small D, Verdi J, Maciag T, Prudovsky I. 2008. Novel cross-talk between three cardiovascular regulators: thrombin cleavage fragment of Jagged1 induces fibroblast growth factor 1 expression and release. Mol Biol Cell. 19: 4863-4874. books

Urs S, Roudabush A, O'Neill CF, Pinz I, Prudovsky I, Kacer D, Tang Y, Liaw L, Small D. 2008. Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes. Am J Pathol. 173: 865-878. books

Lee CW, Raskett CM, Prudovsky I, Altieri DC. 2008. Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis. Cancer Res. 68: 5273-5281. books

Nikopoulos GN, Adams TL, Adams D, Oxburgh L, Prudovsky I, Verdi JM. 2008. The use of Endo-Porter to deliver morpholinos in kidney organ culture. Biotechniques 44: 547-549. books

Leclair RJ, Wang Q, Benson MA, Prudovsky I, Lindner V. 2008. Intracellular localization of Cthrc1 characterizes differentiated smooth muscle. Arterioscler Thromb Vasc Biol. 28: 1332-1338. books

Di Serio C, Doria L, Pellerito S, Prudovsky I, Micucci I, Massi D, Landriscina M, Marchionni N, Masotti G, Tarantini F. 2008. The release of fibroblast growth factor-1 from melanoma cells requires copper ions and is mediated by phosphatidylinositol 3-kinase/Akt intracellular signaling pathway. Cancer Lett. 267: 67-74. books

Prudovsky I, Tarantini F, Landriscina M, Neivandt D, Soldi R, Kirov A, Small D, Kathir KM, Rajalingam D, Kumar TK. 2008. Secretion without Golgi. J Cell Biochem. 103: 1327-1343. books

Kathir KM, Ibrahim K, Rajalingam D, Prudovsky I, Yu C, Kumar TK. 2007. S100A13-lipid interactions-role in the non-classical release of the acidic fibroblast growth factor. Biochim Biophys Acta. 1768: 3080-3089. books

Nikopoulos GN, Duarte M, Kubu CJ, Bellum S, Friesel R, Maciag T, Prudovsky I, Verdi JM. 2007. Soluble Jagged1 attenuates lateral inhibition, allowing for the clonal expansion of neural crest stem cells. Stem Cells. 25: 3133-3142. books


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