Recent Publications from the Perrin Lab

Research Publications Immunology Pharmacology

 

Salvador R, Aridgides D, PereiraPerrin M. 2014. Parasite-derived neurotrophic factor/trans-sialidase of Trypanosoma cruzi links neurotrophic signaling to cardiac innate immune response. Infect Immun. 82: 3687-3696. books

Aridgides D, Salvador R, Pereiraperrin M. 2013. Trypanosoma cruzi coaxes cardiac fibroblasts into preventing cardiomyocyte death by activating nerve Growth Factor Receptor TrkA. PLoS One 8: e57450. books

Aridgides D, Salvador R, Pereiraperrin M. 2013. Trypanosoma cruzi highjacks TrkC to enter cardiomyocytes and cardiac fibroblasts while exploiting TrkA for cardioprotection against oxidative stress. Cell Microbiol. 15: 1357-1366. books

Weinkauf C, Salvador R, Pereiraperrin M. 2011. Neurotrophin receptor TrkC is an entry receptor for Trypanosoma cruzi in neural, glial, and epithelial cells. Infect Immun. 79: 4081-4087. books

PereiraPerrin M. 2011. That’s amore: Bone marrow cells compete for the heart in Chagas disease. News and Views. Cell Cycle 10: 2251.

Chuenkova MV, PereiraPerrin M. 2011. Neuroregeneration and neurodegeneration in Chagas disease. Adv Parasitol. 76: 195-233. books

Lu B, Luquetti AO, Rassi A, PereiraPerrin M. 2010. Autoantibodies to neurotrophic receptors TrkA, TrkB and TrkC in patients with acute Chagas' disease. Scand J Immunol. 71: 220-225. books

Chuenkova MC, PereiraPerrin M. 2009. Chagas’ disease parasite targets host cell Akt kinase in a novel intracellular anti-apoptotic strategy. Science Signaling 2: ra74. books

Weinkauf C, PereiraPerrin M. 2009. Trypanosoma cruzi promotes neuronal and glial cell survival through the neurotrophic receptor TrkC. Infect Immun 77: 1368-1375. books

Caradonna K, PereiraPerrin M. 2009. Preferential brain homing following intranasal administration of Trypanosoma cruzi. Infect Immun 77: 1349-1356. books

Lu B, Alroy J, Luquetti AO, PereiraPerrin M. 2008. Human autoantibodies specific for neurotrophin receptors TrkA, TrkB, and TrkC protect against lethal Trypanosoma cruzi infection in mice. Am J Pathol 173: 1406-1414. books

Lu B, PereiraPerrin M. 2008. A novel immunoprecipitation strategy identifies a unique functional mimic of the GDNF family ligands in the pathogen Trypanosoma cruzi. Infect. Immun. 76: 3530-3538. books

Akpan N, Caradonna K, Chuenkova MV, PereiraPerrin M. 2008. Chagas' disease parasite-derived neurotrophic factor activates cholinergic gene expression in neuronal PC12 cells. Brain Res 1217: 195-202. books

Lu B, Petrola Z, Luquetti AO, PereiraPerrin M. 2008. Auto-antibodies to receptor tyrosine kinases TrkA, TrkB and TrkC in patients with chronic Chagas' disease. Scand J Immunol 67: 603-609. books

de Melo-Jorge M, PereiraPerrin M. 2007. The Chagas' disease parasite Trypanosoma cruzi exploits nerve growth factor receptor TrkA to infect mammalian hosts. Cell Host & Microbe 1: 251-261. books

Bhat N, Joe A, PereiraPerrin M, Ward HD. 2007. Cryptosporidium p30, a galactose/N-acetylgalactosamine-specific lectin, mediates infection in vitro. J Biol Chem. 282: 34877-34887. books

Chuenkova MV, PereiraPerrin M. 2006. Enhancement of tyrosine hydroxylase expression and activity by Trypanosoma cruzi parasite-derived neurotrophic factor. Brain Res 1099: 167-175. books

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