Recent Publications from the Panjwani Lab

Research Publications Cell Biology Immunology


Chen WS, Cao Z, Leffler H, Nilsson UJ, Panjwani N. 2017. Galectin-3 inhibition by a small-molecule inhibitor reduces both pathological corneal neovascularization and fibrosis. Invest Opthalmol Vis Sci. 58: 9-20.  books

Chen WS, Cao Z, Sugaya S, Lopez MJ, Sendra VG, Laver N, Leffler H, Nilsson UJ, Fu J, Song J, Xia L, Hamrah P, Panjwani N. 2016. Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3. Nat Commun. 7: 11302. books

Chen WS, Cao Z, Krishnan C, Panjwani N. 2015. Verteporfin without light stimulation inhibits YAP activation in trabecular meshwork cells: Implications for glaucoma treatment. Biochim Biophys Res Commun. 466: 221-225. books

Sampson JF, Suryawanshi A, Chen WS, Rabinovich GA, Panjwani N. 2015. Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGFβ signaling. Immunol Cell Biol. 94: 213-219.   books

Sampson JF, Hasegawa E, Mulki L, Suryawanshi A, Jiang S, Chen WS, Rabinovich GA, Connor KM, Panjwani N. 2015. Galectin-8 ameliorates murine autoimmune ocular pathology and promotes a regulatory T cell response. PLoS One 10: e130772.  books

Sugaya S, Chen WS, Cao Z, Kenyon KR, Yamaguchi T, Omoto M, Hamrah P, Panjwani N. 2015. Comparison of galectin expression signatures in rejected and accepted murine corneal allografts. Cornea 34: 675-681. books

Chen W, Cao Z, Truong L, Sugaya S, Panjwani N. 2015. Fingerprinting of galectins in normal, P. aeruginosa-infected and chemically burned mouse corneas. Invest Ophthalmol Vis Sci. 56: 515-525. books

Suryawanshi A, Cao Z, Sampson JF, Panjwani N. 2015. IL-17A-mediated protection against Acanthamoeba keratitis. J Immunol. 194: 650-663. books

Panjwani N. 2014. Role of galectins in re-epithelialization of wounds. Ann Transl Med.2: 89. books

Cao Z, Saravanan C, Chen WS, Panjwani N. 2014. Examination of the role of galectins in cell migration and re-epithelialization of wounds. Methods Mol Biol. 1207:317-326. books

Markowska AI, Cao Z, Panjwani N. 2014. Glycobiology of ocular angiogenesis. Glycobiology 24: 1275-1282. books

Suryawanshi A, Cao Z, Thitiprasert T, Zaidi TS, Panjwani N. 2013. Galectin-1-mediated suppression of Pseudomonas aeruginosa-induced corneal immunopathology. J Immunol. 190: 6397-6409. books

Diskin S, Chen WS, Cao Z, Gyawali S, Gong H, Soza A, González A, Panjwani N. 2012. Galectin-8 promotes cytoskeletal rearrangement in trabecular meshwork cells through activation of Rho signaling. PLoS One 7: e44400. books

Markowska AI, Jefferies KC, Panjwani N.  2011. Galectin-3 protein modulates cell surface expression and activation of vascular endothelial growth factor receptor 2 in human endothelial cells. J Biol Chem. 286: 29913-29921. books

Argüeso P, Panjwani N. 2011. Focus on molecules: galectin-3. Exp Eye Res. 92: 2-3. books

Markowska AI, Liu FT, Panjwani N. 2010. Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med. 207: 1981-1993. books

Otri AM, Mohammed I, Abedin A, Cao Z, Hopkinson A, Panjwani N, Dua HS. 2010. Antimicrobial peptides expression by ocular surface cells in response to Acanthamoeba castellanii: an in vitro study. Br J Ophthalmol. 94:1523-1527.  books

Panjwani, N. 2010. Pathogenesis of acanthamoeba keratitis. Ocul Surf. 8: 70-79. books

Saravanan C, Cao Z, Head SR, Panjwani N. 2010. Analysis of differential expression of glycosyltransferases in healing corneas by glycogene microarrays. Glycobiology 20: 13-23. books

Saravanan C, Liu FT, Gipson IK, Panjwani N. 2009. Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on α3β1 integrin. J Cell Sci. 122: 3684-3693. books

Saravanan C, Cao Z, Head SR, Panjwani N. 2009. Detection of differentially expressed wound-healing-related glycogenes in galectin-3-deficient mice. Invest Ophthalmol Vis Sci. 50: 5690-5696. books

Argüeso P, Guzman-Aranguez A, Mantelli F, Cao Z, Ricciuto J, Panjwani N. 2009. Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier.J Biol Chem. 284: 23037-23045. books 

Diskin S, Cao Z, Leffler H, Panjwani N. 2008. The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. Glycobiology 19: 29-37. books

Diskin S, Panjwani N. 2008. Carbohydrate-based recognition systems in primary open angle glaucoma.  Curr Org Chem. 12:  911-917.

Saravanan C, Cao Z, Kumar J, Qiu J, Plaut A, Newburg D, Panjwani N. 2008. Milk components inhibit Acanthamoeba-induced cytopathic effect. Invest Ophthalmol Vis Sci. 49: 1010-1015. books

Cao Z, Saravanan C, Goldstein MH, Wu HK, Pasricha G, Sharma S, Panjwani N. 2008.  Human tears inhibit Acanthamoeba-induced cytopathic effect.  Arch Ophthalmol. 126: 348-352. books

Garate M, Alizadeh H, Neelam S, Niederkorn J, Panjwani N.  2006. Oral immunization with Acanthamoeba mannose-binding protein provides protection against amoebic keratitis.  Infect Immun. 74: 7032-7034. books

Diskin S, Kumar J, Cao Z, Schuman JS, Gilmartin T, Head SR, Panjwani N. 2006. Detection of differentially expressed glycogenes in trabecular meshwork of eyes with primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 47: 1491-1499. books

Garate M, Marchant J, Cubillos I, Cao Z, Khan NA, Panjwani N.  2006. In vitro pathogenicity of Acanthamoeba is associated with the expression of the mannose-binding protein. Invest Ophthalmol Vis Sci. 47: 1056-1062. books

Garate M, Cubillos I, Marchant J, Panjwani N.  2005. Biochemical characterization and functional studies of Acanthamoeba mannose-binding protein. Infect Immun. 73: 5775-5781. books

Garate M, Cao Z, Bateman E, Panjwani N.  2004. Cloning and characterization of a novel mannose-binding protein of Acanthamoeba. J Biol Chem. 279: 29849-29856.books

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