Recent Publications from the Ng Lab

Research Publications Microbiology


Hawver LA, Giulietti JM, Baleja JD, Ng WL. 2016. Quorum sensing coordinates cooperative expression of pyruvate metabolism genes to maintain a sustainable environment for population stability. MBio 7: pii: e01863-016. books

Hawver LA, Jung SA, Ng WL. 2016. Specificity and complexity in bacterial quorum-sensing systems. FEMS Microbiol Rev. Epub ahead of print. books

Jung SA, Hawver LA, Ng WL. 2015. Parallel quorum sensing signaling pathways in Vibrio cholerae. Curr Genet. 62: 255-260. books

Jung SA, Chapman CA, Ng WL 2015. Quadruple quorum-sensing inputs control Vibrio cholerae virulence and maintain system robustness. PLoS Pathog. 11: e1004837. books

Perez LJ, Ng WL, Marano P, Brook K, Bassler BL, Semmelhack MF. 2012.  The role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response. J Med Chem. Epub 55: 9669-9681. books

Ng WL, Perez L, Cong J, Semmelhack MF, Bassler BL. 2012. Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios. PLoS Pathog. 8: e1002767 books

Wei Y, Ng WL, Cong J, Bassler BL. 2012. Ligand and antagonist driven regulation of the Vibrio cholerae quorum-sensing receptor CqsS. Mol Micrbiol. 83: 1095-1108. books

Ng WL, Perez LJ, Wei Y, Kraml C, Semmelhack MF, Bassler BL. 2011. Signal production and detection specificity in Vibrio CqsA/CqsS quorum-sensing systems. Mol Microbiol. 796: 1407-1417. books

Bolitho ME, Perez LJ, Koch MJ, Ng WL, Bassler BL, Semmelhack MF. 2011. Small molecule probes of the receptor binding site in the Vibrio cholerae CAI-1 quorum sensing circuit. Bioorg Med Chem. 19: 6906-6918 books

Wei Y, Perez LJ, Ng WL, Semmelhack MF, Bassler BL. 2011. Mechanism of Vibrio cholerae autoinducer-1 biosynthesis. ACS Chem Biol. 15: 356-365. books

Ng WL, Wei Y, Perez LJ, Cong J, Long T, Koch M, Semmelhack MF, Wingreen NS, Bassler BL. 2011. Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules. Proc Natl Acad Sci USA 107: 5575-5580. books

Kelly RC, Bolitho ME, Higgins DA, Lu W, Ng WL, Jeffrey PD, Rabinowitz JD, Semmelhack MF, Hughson FM, Bassler BL. 2009. The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA. Nature Chem Biol. 5: 891-895. books

Ng WL, Bassler BL. 2009. Bacterial quorum-sensing network architectures. Annu Rev Genet. 43: 197-222. books

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