Recent Publications from the Munro Lab

Research Publications Cell Biology Microbiology


Ma X, Lu M, Gorman J, Terry DS, Hong X, Zhou Z, Zhao H, Altman RB, Arthos J, Blanchard SC, Kwong PD, Munro JB, Mothes W. 2018. HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations. Elife Epub ahead of print. books

Munro JB, Lee KK. 2017. Probing structural variation and dynamics in the HIV-1 Env fusion glycoprotein. Curr HIV Res. Epub ahead of print. books

Do Kwon Y, Pancera M, Acharya P, Georgiev IS, Crooks ET, Gorman J, Joyce MG, Guttman M, Ma X, Narpala S, Soto C, Terry DS, Yang Y, Zhou T, Ahlsen G, Bailer RT, Chambers M, Chuang GY, Doria-Rose NA, Druz A, Hallen MA, Harned A, Kirys T, Louder MK, O'Dell S, Ofek G, Osawa K, Prabhakaran M, Sastry M, Stewart-Jones GB, Stuckey J, Thomas PV, Tittley T, Williams C, Zhang B, Zhao H, Zhou Z, Donald BR, Lee LK, Zolla-Pazner S, Baxa U, Schön A, Freire E, Shapiro L, Lee KK, Arthos J, Munro JB, Blanchard SC, Mothes W, Binley JM, McDermott AB, Mascola JR, Kwong PD. 2015. Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nat Struct Biol. 22: 522-531. books

Munro JB, Mothes W. 2015. Structure and dynamics of the native HIV-1 Env trimer. J Virol. 89: 5752-5755. books

Munro JB, Gorman J, Ma X, Zhou Z, Arthos J, Burton DR, Koff WC, Coulter JC, Smith AB, Kwong PD, Blanchard SC, Mothes W. 2014. Conformational dynamics of single HIV-1 Env trimers on the surface of native virions. Science 346: 759-763. books

Pancera M, Zhou T, Druz A, Georgiev IS, Soto C, Gorman J, Acharya P, Ofek G, Stewart-Jones GBE, Stuckey J, Bailer RT, Chuang GY, Joyce MG, Yang Y, Zhang B, Louder MK, Mascola JR, Cohen MS, Morris L, Tumba N, Haynes BF, Huang J, Connors M, Munro JB, Blanchard SC, Mothes W, Kwong PD. 2014. Structure and immune recognition of a mature HIV-1 Env trimer. Nature 514: 455-561. books

Uchil PD, Pawliczek T, Reynolds TD, Ding S, Hinz A, Munro JB, Fang H, Floyd RW, Yang H, Xiong Y, Bewersdorf J, Mothes W. 2013. TRIM15 is a focal adhesion protein required focal adhesion disassembly. J Cell Sci. 127: 3928-3942. books

Munro JB, Mothes W. 2014. The HIV-1 Env trimer in HD. Structure 22: 935. books

Agosto LM, Zhong P, Munro JB, Mothes W. 2014. Highly active anti-retroviral therapies are effective against the high multiplicity of infection observed during HIV-1 cell-to-cell transmission. PLoS Pathogens 10: e1003982. books

Munro JB, Nath A, Farber M, Datta SAK, Rein A, Rhoades E, Mothes W. 2014. A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles. J Virol. 88: 3577-3585. books

Zhong P, Agosto LM, Munro JB, Mothes W. 2013. Cell-to-cell transmission of viruses. Curr Opin Virol. 1: 44-50. books

Budkevich T, Giesebrech J, Altman RB, Munro JB, Mielke T, Nierhaus KH, Blanchard SC, Spahn CMT. 2011. Structure and dynamics of the mammalian ribosomal pretranslocation complex. Mol Cell 44: 214-224. books

Fu J, Munro JB, Blanchard SC, Frank J. 2011. Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation. Proc Natl Acad Sci USA 108: 4817-4821. books

Whitford PC, Altman RB, Geggier PE, Terry DS, Munro JB, Onuchic JN, Spahn CMT, Sanbonmatsu KY, Blanchard SC. 2011. Dynamic views of ribosome function: energy landscapes and ensembles. In The Ribosome: Structure, Function, and Dynamics. Rodnina MV, Wintermeyer W, Green R, Ed. Springer, New York. 

Munro JB, Wasserman MW, Altman RB, Wang L, Blanchard SC. 2010. Correlated conformational events in EF-G and the ribosome regulate translocation. Nat Struc Mol Biol 17: 1470-1477. books

Geggier PE, Dave R, Feldman MB, Terry DS, Altman RB, Munro JB, Blanchard SC. 2010. Conformational sampling of aminoacyl-tRNA during selection on the bacterial ribosome. J Mol Biol. 399: 576-595. books

Munro JB, Altman RB, Tung CS, Sanbonmatsu KY, Blanchard SC. 2010. A fast dynamic mode of the EF-G-bound ribosome. EMBO J. 29: 709-714. books

Munro JB, Altman RB, Tung CS, Cate JHD, Sanbonmatsu KY, Blanchard SC. 2010. Spontaneous formation of the unlocked state of the ribosome is a multistep process. Proc Natl Acad Sci USA  107: 709-714. books

Munro JB, Sanbonmatsu KY, Spahn CMT, Blanchard SC. 2009. Navigating the ribosome’s metastable free energy landscape. Trends Biochem Sci. 34: 390-400. books

Dave R, Altman RB, Terry DS, Munro JB, Geggier PE, Feldman MB, Blanchard SC. 2009. Single-molecule studies of biomolecules. In Wiley Encyclopedia of Chemical Biology, Vol. 4. Begley TP, Ed. Wiley, New York. 

Dave R, Terry DS, Munro JB, Blanchard SC. 2009. Mitigating unwanted photophysical processes for improved single-molecule fluorescence imaging. Biophys J. 96: 2371-2381. books

Munro JB, Vaiana A, Sanbonmatsu KY, Blanchard SC. 2008. A new view of protein synthesis: Mapping the free energy landscape of the ribosome using single-molecule FRET. Biopolymers 89: 565-577. books

Munro JB, Altman RB, O’Connor N, Blanchard SC. 2007. Identification of two distinct hybrid state intermediates on the ribosome. Mol Cell 25: 505-517. books

Bleuit JS, Ma Y, Munro JB, Morrical SW. 2004. Mutations in a conserved motif inhibit single-stranded DNA binding and recombination mediator activities of bacteriophage T4 UvsY protein. J Biol Chem 279: 6077-6086. books

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