Recent Publications from the Munger Lab

Research Publications Cell Biology  Genetics


Liu Z, Pouli D, Alonzo CA, Varone A, Karaliota S, Quinn KP, Münger K, Karalis KP, Georgakoudi I. 2018. Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast. Sci Adv. 4: :eaap9302. books

McBride AA, Münger K. 2018. Expert views on HPV infection. Viruses 10: 2. books

Sharma S, Munger K. 2018. Expression of the cervical carcinoma expressed PCNA regulatory (CCEPR) long noncoding RNA is driven by the human papillomavirus E6 protein and modulates cell proliferation independent of PCNA. Virology 518: 8-13. books

Wallace NA, Münger K. 2018. The curious case of APOBEC3 activation by cancer-associated human papillomaviruses. PLoS Pathog 14: e1006717. books

Chiang C, Pauli EK, Biryukov J, Feister KF, Meng M, White EA, Münger K, Howley PM, Meyers C, Gack MU. 2017. The human papillomavirus E6 oncoprotein targets USP15 and TRIM25 to suppress RIG-I-mediated innate immune signaling. J Virol. Epub ahead of print. books

Soto DR, Barton C, Munger K, McLaughlin-Drubin ME. 2017. KDM6A addiction of cervical carcinoma cell lines is triggered by E7 and mediated by p21CIP1 suppression of replication stress. PLoS Pathog. 13: e1006661. books

White EA, Munger K. 2017. Crowd control: E7 conservation is the key to cancer. Cell 170: 1057-1059. books

Harden ME, Munger K. 2017. Human papillomavirus molecular biology. Mutat Res. 772: 3-12. books

Harden ME, Munger K. 2017. Human papillomavirus 16 E6 and E7 oncoprotein expression alters microRNA expression in extracellular vesicles. Virology 508: 63-69. books

Harden M Munger K. 2017. Perturbation of DROSHA and DICER expression by human papillomavirus 16 oncoproteins. Virology 507: 192-198.  books

Meyers JM, Uberoi A, Grace M, Lambert PF, Munger K. 2017. Cutaneous HPV8 and MmuPV1 E6 proteins target the NOTCH and TGF-β tumor suppressors to inhibit differentiation and sustain keratinocyte proliferation. PLoS Pathog. 13: e100671. books

Harden ME, Prasad N, Griffiths A, Munger K. 2017. Modulation of microRNA-mRNA target pairs by human papillomavirus 16 oncoproteins. mBio 8: e02170-16.  books

Grace M, Munger K. 2016. Proteomic analysis of the gamma human papillomavirus type 197 E6 and E7 associated cellular proteins. Virology 500: 71-81.  books

Munger K. 2016. Viruses and cancer: An accidental journey. PLoS Pathog 12: e1005573.  books

Munger K, Jones DL. 2015. HPV carcinogenesis - An identity crisis in the retinoblastoma tumor suppressor pathway. J Virol. 89: 4708-4711. books

Xylas J, Varone A, Quinn KP, Pouli D, McLaughlin-Drubin ME, Thieu HT, Garcia-Moliner ML, House M, Hunter M, Munger K, Georgakoudi I. 2015. Noninvasive assessment of mitochondrial organization in three-dimensional tissues reveals changes associated with cancer development. Int J Cancer 136: 322-332. books

Meyers JM, Munger K. 2014. The viral etiology of skin cancer. J invest Dermatol. 134: e29-e33. books

Varone A, Xylas J, Quinn KP, Pouli D, Sridharan G, McLaughlin-Drubin ME, Alonzo C, Lee K, Münger K, Georgakoudi I. 2014. Endogenous two-photon fluorescence imaging elucidates metabolic changes related to enhanced glycolysis and glutamine consumption in precancerous epithelial tissues. Cancer Res. 74: 3067-3075. books

Mesri EA, Feitelson MA, Munger K. 2014. Human viral oncogenesis: a cancer hallmarks analysis. Cell Host Microbe 15: 266-282. books

Munger K. 2014. Are selective estrogen receptor modulators (SERMs) a therapeutic option for HPV-associated cervical lesions and cancers? Am J Pathol. 184: 358-361. books

Munger K, Gwin TK, McLaughlin-Drubin ME. 2013. p16 in HPV-associated cancers. Oncotarget 4: 1864-1865. books

Yu Y, Munger K. 2013. Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis. Virology 446: 251-259. books

Mack HI, Munger K. 2013. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines. Virology 446: 9-16. books

McLaughlin-Drubin ME, Park D, Munger K. 2013. Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines. Proc Natl Acad Sci USA 110: 16175-16180. books

Roman A, Munger K. 2013. The papillomavirus E7 proteins. Virology 445: 138-168. books

McLaughlin-Drubin ME, Munger K. 2013. Biochemical and functional interactions of human papillomavirus proteins with polycomb group proteins. Viruses 5: 1231-1249. books

Spangle JM, Munger K. 2013. The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species. PLoS Pathog. 9: e1003237. books

Meyers JM, Spangle JM, Munger K. 2013. The human papillomavirus type 8 E6 protein interferes with NOTCH activation during keratinocyte differentiation. J Virol. 87: 4762-4767. books

Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC, Ficarro SB, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL, Beroukhim R, Kieff E, Cusick ME, Hill DE, Münger K, Marto JA, Quackenbush J, Roth FP, DeCaprio JA, Vidal M. 2012. Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature 487: 491-495. books

Gulbahce N, Yan H, Dricot A, Padi M, Byrdsong D, Franchi R, Lee DS, Rozenblatt-Rosen O, Mar JC, Calderwood MA, Baldwin A, Zhao B, Santhanam B, Braun P, Simonis N, Huh KW, Hellner K, Grace M, Chen A, Rubio R, Marto JA, Christakis NA, Kieff E, Roth FP, Roecklein-Canfield J, Decaprio JA, Cusick ME, Quackenbush J, Hill DE, Münger K, Vidal M, Barabási AL. 2012. Viral perturbations of host networks reflect disease etiology. PLoS Comput Biol. 8: e1002531. books

Yu Y, Munger K. 2012. Human papillomavirus type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint. Virology 432: 120-126. books

Herfs M, Yamamoto Y, Laury A, Wang X, Nucci MR, McLaughlin-Drubin ME, Münger K, Feldman S, McKeon FD, Xian W, Crum CP. 2012. A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proc Natl Acad Sci USA 109: 10516-10521. books

McLaughlin-Drubin ME, Meyers J, Munger K. 2012. Cancer associated human papillomaviruses. Curr Opin Virol. 2: 459-466. books

Spangle JM, Ghosh-Choudhury N, Munger K. 2012. Activation of cap-dependent translation by mucosal human papillomavirus E6 proteins is dependent on the integrity of the LXXLL binding motif. J Virol. 86: 7466-7472. books

White EA, Sowa ME, Tan MJ, Jeudy S, Hayes SD, Santha S, Münger K, Harper JW, Howley PM. 2012. Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses. Proc Natl Acad Sci USA 109: E260-W267. books

Mack HI, Munger K. 2012. Modulation of autophagy-like processes by tumor viruses. Cells 1: 204-247. books

Levitt JM, McLaughlin-Drubin ME, Münger K, Georgakoudi I. 2011. Automated biochemical, morphological, and organizational assessment of precancerous changes from endogenous two-photon fluorescence images. PLoS One 6: e24765. books

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