Recent Publications from the Malamy Lab

Research Publications Genetics Microbiology

 

Hess V, Gallegos R, Jones JA, Barquera B, Malamy MH, Müller V. 2016. Occurrence of ferredoxin:NAD(+) oxidoreductase activity and its ion specificity in several Gram-positive and Gram-negative bacteria. PeerJ 4: e1515.  books

Meehan BM, Baughn AD, Gallegos R, Malamy MH. 2012. Inactivation of a single gene enables microaerobic growth of the obligate anaerobe Bacteroides fragilis. Proc Natl Acad Sci USA 109: 12153-12158. books

Meehan BM, Malamy MH.  2012. Fumarate reductase is a major contributor to the generation of reactive oxygen species in the anaerobe Bacteroides fragilis. Microbiology. 158: 539-546. books

Brigham C, Caughlan R, Gallegos R, Dallas MB, Godoy VG, Malamy MH. 2009. Sialic acid (N-acetyl neuraminic acid) utilization by Bacteroides fragilis requires a novel N-acetyl mannosamine epimerase. J Bacteriol. 191: 3629-2638. books

Shi D, Morizono H, Cabrera-Luque J, Yu X, Roth L, Malamy MH, Allewell NM, Tuchman M. 2006. Structure and catalytic mechanism of a novel N-succinyl-L-ornithine transcarbamylase in arginine biosynthesis of Bacteroides fragilis.  J Biol Chem 281: 20623-20631. books

Morizono H, Cabrera-Luque J, Shi D, Gallegos R, Yamaguchi S, Yu X, Allewell NM, Malamy MH, Tuchman M. 2006. Acetylornithine transcarbamylase: a novel enzyme in arginine biosynthesis. J Bacteriol. 188: 2974-2982. books

Shi D, Morizono H, Yu X, Roth L, Caldovic L, Allewell NM, Malamy MH, Tuchman M. 2005. Crystal structure of N-acetylornithine transcarbamylase from Xanthomonas campestris: a novel enzyme in a new arginine biosynthetic pathway found in several eubacteria. J Biol Chem. 280: 14366-14369. books

Brigham, C and M.H. Malamy. 2005. Characterization of the RokA and HexA broad substrate specificity hexokinases from Bacteroides fragilis and their role in hexose and N-acetylglucosamine utilization. J Bacteriol 187: 890-901. books

Baughn A.D. and M.H. Malamy. 2004. The strict anaerobe Bacteroides fragilis grows in and benefits from nanomolar concentrations of oxygen. Nature. 427:441-444. books

Baughn A.D. and M.H. Malamy. 2003. The essential role of fumarate reductase in haem-dependent growth stimulation of Bacteroides fragilis. Microbiology 149:1551-1558. books

Shi D, Gallegos R, DePonte J 3rd, Morizono H, Yu X, Allewell NM, Malamy M, Tuchman M. 2002. Crystal structure of a transcarbamylase-like protein from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution. J Mol Biol. 320: 899-908. books

Caldovic L, Morizono H, Yu X, Thompson M, Shi D, Gallegos R, Allewell NM, Malamy MH, Tuchman M. 2002. Identification, cloning and expression of the mouse N-acetylglutamate synthase gene. Biochem J. 364: 825-831. books

Baughn AD, Malamy MH. 2002. From the Cover: A mitochondrial-like aconitase in the bacterium Bacteroides fragilis: Implications for the evolution of the mitochondrial Krebs cycle. Proc Natl Acad Sci USA 99: 4662-4667. books

Chen T, Dong H, Tang YP, Dallas MM, Malamy MH, Duncan MJ. 2000. Identification and cloning of genes from Porphyromonas gingivalis after mutagenesis with a modified Tn4400 transposon from Bacteroides fragilis. Infect Immun. 68: 420-423. books

Tang YP, Malamy MH. 2000. Isolation of Bacteroides fragilis mutants with in vivo growth defects by using Tn4400', a modified Tn4400 transposition system, and a new screening method. Infect Immun. 68: 415-419. books

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