Recent Publications from the Chen Lab

Research Publications Pharmacology

 

Waghorn PA, Jones CM, Rotile NJ, Koerner SK, Ferreira DS, Chen HH, Probst CK, Tager AM, Caravan P. 2017. Molecular magnetic resonance imaging of lung fibrogenesis with an oxyamine-based probe. Angew Chem Int Ed Engl. 56: 9825-9828. books

Chen HH, Waghorn PA, Wei L, Tapias LF, Schu Hle DT, Rotile NJ, Jones CM, Looby RJ, Zhao G, Elliott JM, Probst CK, Mino-Kenudson M, Lauwers GY, Tager AM, Tanabe KK, Lanuti M, Fuchs BC, Caravan P. 2017. Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis. JCI Insight Epub ahead of print. books

Chen HH, Yuan H, Cho H, Feng Y, Ngoy S, Kumar AT, Liao R, Chao W, Josephson L, Sosnovik DE. 2017. Theranostic nucleic acid binding nanoprobe exerts anti-inflammatory and cytoprotective effects in ischemic injury. Thernostics 7: 814-825. books

Goergen CJ, Chen HH, Sakadžić S, Srinivasan VJ, Sosnovik DE. 2016. Microstructural characterization of myocardial infarction with optical coherence tractography and two-photon microscopy. Physiol Rep. pii: e12894. doi: 10.14814/phy2.12894. books

Panagia M, Chen YC, Chen HH, Ernande L, Chen C, Chao W, Kwong K, Scherrer-Crosbie M, Sosnovik DE. 2016. Functional and anatomical characterization of brown adipose tissue in heart failure with blood oxygen level dependent magnetic resonance. NMR Biomed. 29: 978-984 books

Zou L, Chen HH, Li D, Xu G, Feng Y, Chen C, Wang L, Sosnovik DE, Chao W. 2015. Imaging lymphoid cell death in vivo during polymicrobial sepsis. Crit Care Med. 43: 2303-2312. books

Normandin MD, Yuan H, Wilks MQ, Chen HH, Kinsella JM, Cho H, Guehl NJ, Absi-Halabi N, Hosseini SM, El Fakhri G, Sosnovik DE, Josephson L. 2015. Heat-induced radiolabeling of nanoparticles for monocyte tracking by PET. Angew Chemie Int Ed Engl. 54: 13002-13006 books

Chen HH, Yuan H, Cho H, Sosnovik DE, Josephson L. 2015. Cytoprotective nanoparticles by conjugation of a polyhis tagged annexin V to a nanoparticle drug. Nanoscale 7: 2255-2259. books

Liu Y, Asnani A, Zou L, Bentley VL, Yu M, Wang Y, Dellaire G, Sarkar KS, Dai M, Chen HH, Sosnovik DE, Shin JT, Haber DA, Berman JN, Chao W, Peterson RT. 2014. Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase. Sci Transl Med. 6: 266ra170. books

Figge L, Appler F, Chen HH, Sosnovik DE, Schnorr J, Seitz O, Taupitz M, Hamm B, Schellenberger E. 2014. Direct coupling of annexin A5 to VSOP yields small, protein-covered nanoprobes for MR imaging of apoptosis. Contrast Media Mol imaging 9: 291-299. books

Sosnovik DE, Mekkaoui C, Huang S, Chen HH, Dai G, Stoeck CT, Ngoy S, Guan J, Wang R, Kostis WJ, Jackowski MP, Wedeen VJ, Kozerke S, Liao R. 2014. Microstructural impact of ischemia and bone marrow-derived cell therapy revealed with diffusion tensor magnetic resonance imaging tractography of the heart in vivo. Circulation 129: 1731-1741 books

Chen C, Feng Y, Zou L, Wang L, Chen HH, Cai JY, Xu JM, Sosnovik DE, Chao W. 2014. Role of extracellular RNA and TLR3-Trif signaling in myocardial ischemia-reperfusion injury. J Am Heart Assoc. 3: e000683. books

Caravan P, Yang Y, Zachariah R, Schmitt A, Mino-Kenudson M, Chen HH, Sosnovik DE, Dai G, Fuchs BC, Lanuti M. 2013. Molecular magnetic resonance imaging of pulmonary fibrosis in mice. Am J Respir Cell Mol Biol. 49: 1120-1126.  books

Yuan H, Cho H, Chen HH, Panagia M, Sosnovik DE, Josephson L. 2013. Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria. Chem Commun. 49: 10361-10363. books

Chen HH, Mekkaoui C, Cho H, Ngoy S, Marinelli B, Waterman P, Nahrendorf M, Liao R, Josephson L, Sosnovik DE. 2013. Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo. Circ Cardiovasc Imaging 6: 441-447. books

Cho H, Alcantara D, Yuan H, Sheth RA, Chen HH, Huang P, Andersson SB, Sosnovik DE, Mahmood U, Josephson L. 2013. Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems. ACS Nano 7: 203302041. books

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