Recent Publications from the Garlick Lab

Research Publications Cell Biology


Garlick JA, Levine P. 2017. Where civics meets science: building science for the public good through Civic Science. Oral Dis. 23: 692-696. books

Chen CO, Smith A, Liu Y, Du P, Blumberg JB, Garlick J. 2017. Photoprotection by pistachio bioactives in a 3-dimensional human skin equivalent tissue model. Int J Food Sci Nutr. 25: 1-9. books

Higgins CA, Roger M, Hill R, Ali-Khan AS, Garlick J, Christiano AM, Jahoda CA. 2017. Multifaceted role of hair follicle dermal cells in bioengineered skins. Br J Dermatol. 176: 1259-1269. books

Higgins CA, Roger M, Hill R, Ali-Khan AS, Garlick J, Christiano AM, Jahoda CA. 2016. Multifaceted role of hair follicle dermal cells in bioengineered skins. Br J Dermatol. Epub ahead of print. books

Liang L, Stone RC, Stojadinovic O, Ramirez H, Pastar I, Maione AG, Smith A, Yanez V, Veves A, Kirsner RS, Garlick JA, Tomic-Canic M. 2016. Integrative analysis of miRNA and mRNA paired expression profiling of primary fibroblast derived from diabetic foot ulcers reveals multiple impaired cellular functions. Wound Regen Repair 24: 943-953.  books

Garlick J, Levine P. 2016. Where civics meets science: Building science for the public good through civic science. Oral Dis. Epub ahead of print. books

Gerami-Naini B, Smith A, Maione AG, Kashpur O, Carpinito G, Veves A, Mooney DJ, Garlick JA. 2016. Generation of induced pluripotent stem sells from diabetic foot ulcer fibroblasts using a nonintegrative Sendai virus. Cell Reprogram. 18: 214-223. books

Maione AG, Smith A, Kashpur O, Yanez V, Knight E, Mooney DJ, Veves A, Tomic-Canic M, Garlick JA. 2016. Altered ECM deposition by diabetic foot ulcer-derived fibroblasts implicates fibronectin in chronic wound repair. Wound Repair Regen. 24: 630-643.  books

Ramirez HA, Liang L, Pastar I, Rosa AM, Stojadinovic O, Zwick TG, Kirsner RS, Maione AG, Garlick JA, Tomic-Canic M. 2015. Comparative genomic, microRNA, and tissue analyses reveal subtle differences between non-diabetic and diabetic foot skin. PLoS One 10 : e0137133.  books

Park LK, Maione AG, Smith A, Gerami-Naini B, Iyer LK, Mooney DJ, Veves A, Garlick JA. 2014. Genome-wide DNA methylation analysis identifies a metabolic memory profile in patient-derived diabetic foot ulcer fibroblasts. Epigenetics 9: 1339-1349. books

Hewitt KJ, Shamis Y, Gerami-Naini B, Garlick JA. 2014. Strategies for oral mucosal repair by engineering 3D tissues with pluripotent stem cells. Adv Wound Care (New Rochelle) 3: 742-750.  books

Maione AG, Brudno Y, Stojadinovic O, Park LK, Smith A, Tellechea A, Leal EC, Kearney CJ, Veves A, Tomic-Canic M, Mooney D, Garlick J. 2014. 3D human tissue models that incorporate diabetic foot ulcer-derived fibroblasts mimic in vivo features of chronic wounds. Tissue Eng Part C Methods 21: 499-508.  books

Shamis Y, Silva EA, Hewitt KJ, Brudno Y, Levenberg S, Mooney DJ, Garlick JA. 2013. Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo. PLoS One 8: e83755. books

Evans-Johnson JA, Garlick JA, Johnson EJ, Wang XD, Oliver Chen CY. 2013. A pilot study of the photoprotective effect of almond phytochemicals in a 3D human skin equivalent. J Photochem Photobiol B. 126: 17-25. books

Lucier RN, Etienne O, Ferreira S, Garlick JA, Kugel G, Egles C. 2013. Soft-tissue alterations following exposure to tooth-whitening agents. J Periodontol. 84: 513-519. books

Bellas E, Seiberg M, Garlick J, Kaplan DL. 2012. In vitro 3D full-thickness skin-equivalent tissue model using silk and collagen biomaterials. Macromol Biosci. 12: 1627-1636. books

Hewitt KJ, Garlick JA. 2012. Cellular reprogramming to reset epigenetic signatures. Mol Aspects Med. 34: 841-848. books

Lucier R, Etienne O, Ferreira S, Garlick J, Kugel G, Egles C. 2012. Soft tissue alterations following exposure to tooth whitening agents(*). J Peridontol. 84: 513-519. books

Wittmer CR, Claudepierre T, Reber M, Wiedemann P, Garlick JA, Kaplan D, Egles C. 2011. Multifunctionalized electrospun silk fibers promote axon regeneration in central nervous system. Adv Funct Mater. 21: 4202. books

Keller PJ, Arendt LM, Skibinski A, Logvinenko T, Klebba I, Dong S, Smith AE, Prat A, Perou CM, Gilmore H, Schnitt S, Naber SP, Garlick JA, Kuperwasser C. 2012. Defining the cellular precursors to human breast cancer. Proc Natl Acad Sci U S A. 109: 2772-2777. books

Hewitt KJ, Shamis Y, Knight E, Smith A, Maione A, Alt-Holland A, Sheridan SD, Haggarty SJ, Garlick JA. 2012. PDGFRβ Expression and Function in Fibroblasts Derived from Pluripotent Cells is Linked to DNA Demethylation. J Cell Sci. 125 (Pt9): 2276-2287. books

Shamis Y, Hewitt KJ, Bear SE, Alt-Holland A, Qari H, Margvelashvilli M, Knight EB, Smith A, Garlick JA.  2012. iPSC-derived fibroblasts demonstrate augmented production and assembly of extracellular matrix proteins. In Vitro Cell Dev Biol Anim. 48: 112-122. books

Desrochers TM, Shamis Y, Alt-Holland A, Kudo Y, Takata T, Wang G, Jackson-Grusby L, Garlick JA.  2012. The 3D tissue microenvironment modulates DNA methylation and E-cadherin expression in squamous cell carcinoma. Epigenetics. 7: 34-46. books

Alt-Holland A, Sowalsky AG, Szwec-Levin Y, Shamis Y, Hatch H, Feig LA, Garlick JA. 2011. Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src. J Invest Dermatol. 131: 2306-2315. books

Carlson MW, Garlick JA, Solomon LW. 2011. Chronic ulcerative stomatitis: evidence of autoimmune pathogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 111: 742-748. books

Hewitt KJ, Shamis Y, Hayman RB, Margvelashvili M, Dong S, Carlson MW, Garlick JA. 2011. Epigenetic and phenotypic profile of fibroblasts derived from induced pluripotent stem cells. PLoS One 6: e17128. books

Shamis Y, Hewitt KJ, Carlson MW, Margvelashvilli M, Dong S, Kuo CK, Daheron L, Egles C, Garlick JA. 2011. Fibroblasts derived from human embryonic stem cells direct development and repair of 3D human skin equivalents. Stem Cell Res Ther. 21: 10. books

Sowalsky AG, Alt-Holland A, Shamis Y, Garlick JA, Feig LA. 2011. RalA function in dermal fibroblasts is required for the progression of squamous cell carcinoma of the skin. Cancer Res. 71: 758-767. Abstract in PubMed

Gomes HJ, Dong S, Wein RO, Garlick JA. 2010. Fabrication of 3-dimensional tissue models to study head and neck squamous cell carcinoma. Laryngoscope 120: S142. books

Xu K, Rajagopal S, Klebba I, Dong S, Ji Y, Liu J, Kuperwasser C, Garlick JA, Naber SP, Buchsbaum RJ. 2010. The role of fibroblast Tiam1 in tumor cell invasion and metastasis. Oncogene 29: 6533-6542. books

Egles C, Huet HA, Dogan F, Cho S, Dong S, Smith A, Knight EB, McLachlan KR, Garlick JA. 2010. Integrin-blocking antibodies delay keratinocyte re-epithelialization in a human three-dimensional wound healing model. PLoS One 5: e10528. books

Egles C, Garlick JA, Shamis Y. 2010.  Three-dimensional human tissue models of wounded skin. Methods Mol Biol. 585: 345-359.  books

Etienne O, Schneider A, Kluge JA, Bellemin-Laponnaz C, Polidori C, Leisk GG, Kaplan DL, Garlick JA, Egles C. 2009. Soft tissue augmentation using silk gels: an in vitro and in vivo study. J Periodontol. 80: 1852-1858. books

Sowalsky AG, Alt-Holland A, Shamis Y, Garlick JA, Feig LA. 2010. RalA suppresses early stages of Ras-induced squamous cell carcinoma progression. Oncogene 29: 45-55. Abstract in PubMed

Hewitt KJ, Shamis Y, Carlson MW, Aberdam E, Aberdam D, Garlick JA. 2009. Three-dimensional epithelial tissues generated from human embryonic stem cells. Tissue Eng Part A 15: 3417-3426. books

Schneider A, Wang XY, Kaplan DL, Garlick JA, Egles C. 2009. Biofunctionalized electrospun silk mats as a topical bioactive dressing for accelerated wound healing. Acta Biomater. 5:2570-2578. books

Carlson MW, Alt-Holland A, Egles C, Garlick JA. 2008. Three-dimensional tissue models of normal and diseased skin. Curr Protoc Cell Biol. Chpt 19, Unit 19.9.  books

Alt-Holland A, Shamis Y, Riley KN, DesRochers TM, Fusenig NE, Herman IM, Garlick JA. 2008. E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents. J Invest Dermatol. 128: 2498-2507. books

Egles C, Shamis Y, Mauney JR, Volloch V, Kaplan DL, Garlick JA. 2008. Denatured collagen modulates the phenotype of normal and wounded human skin equivalents. J Invest Dermatol. 128: 1830-1837. books

Schneider A, Garlick JA, Egles C. 2008. Self-assembling peptide nanofiber scaffolds accelerate wound healing. PLoS One 3: e1410. books

Segal N, Andriani F, Pfeiffer L, Kamath P, Lin N, Satyamurthy K, Egles C, Garlick JA. 2008. The basement membrane microenvironment directs the normalization and survival of bioengineered human skin equivalents. Matrix Biol. 27: 163-170. books

Garlick JA. 2007. Engineering skin to study human disease--tissue models for cancer biology and wound repair. Adv Biochem Eng Biotechnol. 103: 207-239. books

Zhang W, Alt-Holland A, Margulis A, Shamis Y, Fusenig NE, Rodeck U, Garlick JA. 2006. E-cadherin loss promotes the initiation of squamous cell carcinoma invasion through modulation of integrin-mediated adhesion. J Cell Sci (Pt2)  119: 283-291. books

Margulis A, Zhang W, Alt-Holland A, Pawagi S, Prabhu P, Cao J, Zucker S, Pfeiffer L, Garfield J, Fusenig NE, Garlick JA. 2006. Loss of intercellular adhesion activates a transition from low- to high-grade human squamous cell carcinoma. Int J Cancer 118: 821-831. books

Greenberg S, Kamath P, Petrali J, Hamilton T, Garfield J, Garlick JA. 2006. Characterization of the initial response of engineered human skin to sulfur mustard. Toxicol Sci. 90: 549-557. Abstract in PubMed

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February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

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June 15: Online Certificate in Fundamentals of Clinical Care Research