Recent Publications from the Galper Lab

Research Publications Cell Biology Physiology

 

Jin H, Welzig CM, Aronovitz M, Noubary F, Blanton R, Wang B, Rajab M, Albano A, Link MS, Noujaim SF, Park HJ, Galper JB. 2017. QRS/T-wave and calcium alternans in a Type I diabetic mouse model for spontaneous post myocardial infarction ventricular tachycardia: A mechanism for the antiarrhythmic effect of statins. heart Rhythm. Epub ahead of print. books

Qin Z, Bagley J, Sukhova G, Baur WE, Park HJ, Beasley D, Libby P, Zhang Y, Galper JB. 2015. Angiotensin II-induced TLR4 mediated abdominal aortic aneurysm in Apolipoprotein E knockout mice is dependent on STAT3. J Mol Cell Cardiol. 87: 160-170. books

Zhang Y, Welzig CM, Picard K, Du C, Wang B, Kyriakis J, Aronovitz M, Claycomb W, Blanton R, Park HJ, Galper JB. 2014. Glycogen synthase kinase-3β inhibition ameliorates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice. Diabetes 63: 2097-2113.  books

Rajab M, Jin H, Welzig CM, Albano A, Aronovitz M, Zhang Y, Park HJ, Link MS, Noujaim SF, Galper JB. 2013. Increased inducibility of ventricular tachycardia and decreased heart rate variability in a mouse model for type 1 diabetes: effect of pravastatin. Am J Physiol Heart Circ Physiol. 305: H1807-H1816. books

Higashimori M, Tatro JB, Moore KJ, Mendelsohn ME, Galper JB, Beasley D. 2011. Role of toll-like receptor 4 in intimal foam cell accumulation in apolipoprotein E-deficient mice. Atheroscler Thromb Vasc Biol. 31: 50-57. books

Welzig CM, Park HJ, Naggar J, Confalone D, Rhofiry J, Shea J, Karas RH, Estes NA 3rd, Galper JB. Differential effects of statins (pravastatin or simvastatin) on ventricular ectopic complexes: Gα(i2), a possible molecular marker for ventricular irritability. Am J Cardiiol. 105: 1112-1117. books

Zhang Y, Naggar JC, Welzig CM, Beasley D, Moulton KS, Park HJ, Galper JB. 2009. Simvastatin inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice: possible role of ERK. Arterioscler Thromb Vasc Biol. 29: 1764-1771. books  

Park HJ, Zhang Y, Du C, Welzig CM, Madias C, Aronovitz MJ, Georgescu SP, Naggar I, Wang B, Kim YB, Blaustein RO, Karas RH, Liao R, Mathews CE, Galper JB. 2009. Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice. Circ Res. 105: 287-294. books

Park HJ, Georgescu SP, Du C, Madias C, Aronovitz MJ, Welzig CM, Wang B, Begley U, Zhang Y, Blaustein RO, Patten RD, Karas RH, Van Tol HH, Osborne TF, Shimano H, Liao R, Link MS, Galper JB. 2008. Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP. J Clin Invest. 118: 259-271. books

Park HJ, Zhang Y, Georgescu SP, Johnson KL, Kong D, Galper JB. 2006. Human umbilical vein endothelial cells and human dermal microvascular endothelial cells offer new insights into the relationship between lipid metabolism and angiogenesis. Stem Cell Rev. 2: 93-102. books

Tang D, Park HJ, Georgescu SP, Sebti SM, Hamilton AD, Galper JB. 2006. Simvastatin potentiates tumor necrosis factor alpha-mediated apoptosis of human vascular endothelial cells via the inhibition of the geranylgeranylation of RhoA. Life Sci. 79: 1484-1492. books

Park HJ, Ward SM, Desgrosellier JS, Georgescu SP, Papageorge AG, Zhuang X, Barnett JV, Galper JB. 2006. Transforming growth factor β regulates the expression of the M2 muscarinic receptor in atrial myocytes via an effect on RhoA and p190RhoGAP. J Biol Chem. 281:1 9995-20002. books

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