Recent Publications from the Cochran Lab

Research Publications Cell Biology  Genetics Pharmacology


Kulkarni S, Goel S, Sengupta S, Cochran BH. 2017. A large-scale RNAi screen identifies SGK1 as a key survival kinase for GBM stem cells. Mol Cancer Res. Epub ahead of print. Abstract in PubMed

Sherry-Lynes MM, Sengupta S, Kulkarni S, Cochran BH. 2017. Regulation of the JMJD3 (KDM6B) histone demethylase in glioblastoma stem cells by STAT3. PLoS One 12: e0174775. Abstract in PubMed

Chakraborty S, Li L, Tang H, Xie Y, Puliyappadamba VT, Raisanen J, Burma S, Boothman DA, Cochran B, Wu J, Habib AA. 2013. Cytoplasmic TRADD confers a worse prognosis in glioblastoma. Neoplasia 15: 888-897. Abstract in PubMed

Mihaliak AM, Gilbert CA, Li L, Daou MC, Moser RP, Reeves A, Cochran BH, Ross AH. 2010. Clinically relevant doses of chemotherapy agents reversibly block formation of glioblastoma neurospheres. Cancer Lett. 296: 168-177. Abstract in PubMed

Carette JE, Guimaraes CP, Varadarajan M, Park AS, Wuethrich I, Godarova A, Kotecki M, Cochran BH, Spooner E, Ploegh HL, Brummelkamp TR. 2009. Haploid genetic screens in human cells identify host factors used by pathogens. Science 326: 1231-1235. Abstract in PubMed

Sherry MM, Reeves A, Wu JK, Cochran BH. 2009. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells 27: 2383-2392. Abstract in PubMed

Simeone-Penney MC, Severgnini M, Rozo L, Takahashi S, Cochran BH, Simon AR. 2008. PDGF-induced human airway smooth muscle cell proliferation requires STAT3 and the small GTPase Rac1. Am J Physiol Lung Cell Mol Physiol. 294: L698-L704. Abstract in PubMed

Konnikova L, Simeone MC, Kruger MM, Kotecki M, Cochran BH. 2005. Signal transducer and activator of transcription 3 (STAT3) regulates human telomerase reverse transcriptase (hTERT) expression in human cancer and primary cells. Cancer Res. 65: 6516-6520. books

Simon AR, Severgnini M, Takahashi S, Rozo L, Andrahbi B, Agyeman A, Cochran BH, Day RM, Fanburg BL. 2005. 5-HT induction of c-fos gene expression requires reactive oxygen species and Rac1 and Ras GTPases. Cell Biochem Biophys. 42: 263-76. books

Severgnini M, Takahashi S, Tu P, Perides G, Homer RJ, Jhung JW, Bhavsar D, Cochran BH, Simon AR. 2005. Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury. Am J Respir Crit Care Med. 171: 858-867. books

Severgnini M, Takahashi S, Rozo LM, Homer RJ, Kuhn C, Jhung JW, Perides G, Steer M, Hassoun PM, Fanburg BL, Cochran BH, Simon AR. 2004. Activation of the STAT pathway in acute lung injury.Am J Physiol Lung Cell Mol Physiol. 286: L1282-L1292. books

Konnikova L, Kotecki M, Kruger MM, Cochran BH. 2003. Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer. 3: 23. books

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