Recent Publications from the Baleja Lab

 

Research Publications Biochemistry Cell Biology

 

Rowan S, Jiang S, Korem T, Szymanski J, Chang ML, Szelog J, Cassalman C, Dasuri K, McGuire C, Nagai R, Du XL, Brownlee M, Rabbani N, Thornalley PJ, Baleja JD, Deik AA, Pierce KA, Scott JM, Clish CB, Smith DE, Weinberger A, Avnit-Sagi T, Lotan-Pompan M, Segal E, Taylor A. 2017. Proc Natl Acad Sci USA Epub ahead of print.  books

Hawver LA, Giulietti JM, Baleja JD, Ng WL. 2016. Quorum sensing coordinates cooperative expression of pyruvate metabolism genes to maintain a sustainable environment for population stability. MBio 7: pii: e01863-16. books

Shearer AM, Rana R, Austin K, Baleja JD, Nguyen N, Bohm A, Covic L, Kuliopulos A. 2016. Targeting liver fibrosis with a cell-penetrating PAR2 pepducin. J Biol Chem. 291: 23188-23198. books

Zhang P, Leger AJ, Baleja JD, Rana R, Corlin T, Nguyen N, Koukos G, Bohm A, Covic L, Kuliopulos A. 2015. Allosteric activation of a G protein coupled receptor with cell-penetrating receptor mimetics. J Biol Chem. 290: 15785-15798. books

Quartararo JS, Eshelman MR, Peraro L, Yu H, Baleja JD, Lin YS, Kritzer JA. 2014. A bicyclic peptide scaffold promotes phosphotyrosine mimicry and cellular uptake. Bioorg Med Chem. 22: 6387-6391.  Abstract in PubMed

Kamens AJ, Eisert RJ, Corlin T, Baleja JD, Kritzer JA. 2014. Structured cyclic peptides that bind the EH domain of EHD1. Biochemistry 53: 4758-4760.  Abstract in PubMed

Cherry JJ, Rietz A, Malinkevich A, Liu Y, Xie M, Bartolowits M, Davisson VJ, Baleja JD, Androphy EJ. 2013. Structure based identification and characterization of flavonoids that disrupt human papillomavirus-16 e6 function. PLoS One 8: e84506. Abstract in PubMed

Liberman R, Cotter K, Baleja JD, Forgac M. 2013. Structural analysis of the N-terminal domain of subunit a of the yeast vacuolar ATPase (V-ATPase) using accessibility of single cysteine substitutions to chemical modification. J Biol Chem. 288: 22798-22808. Abstract in PubMed

Krishnamurthy VM, Raman VS, Mowery RA, Hentz M, Baleja JD, Shaw BF, Kumar K. 2013. Ligand-induced protein mobility in complexes of carbonic anhydrase II and benzenesulfonamides with oligoglycine chains. PLoS One 8: e0057629. books

Clark GA, Baleja JD, Kumar K. 2012. Cross-strand interactions of fluorinated amino acids in β-hairpin constructs. J Am Chem Soc. 134: 17912-17921. books

Zhang P, Gruber A, Kasuda S, Kimmelstiel C, O'Callaghan K, Cox DH, Bohm A, Baleja JD, Covic L, Kuliopulos A. 2012. Suppression of arterial thrombosis without affecting hemostatic parameters with a cell-penetrating PAR1 pepducin. Circulation 126: 83091. books

Moore FB, Baleja JD. 2012. Molecular remodeling mechanisms of the neural somatodendritic compartment. Biochim Biophys Acta. 1823: 1720-1730. books

Nuzzio KM, Cullinan DB, Novakovic VA, Boettcher JM, Rienstra CM, Gilbert GE, Baleja JD.2012. Backbone resonance assignments of the C2 domain of coagulation factor VIII. Biomol NMR Assign. 7: 31-34. books

Badway JA, Baleja JD.  2011. Reps2: A cellular signaling and molecular trafficking nexus. Int J Biochem Cell Biol. 43: 1660-1663. books

Bose K, Meinke G, Bohm A, Baleja JD.  2011. Design and characterization of an enhanced repressor of human papillomavirus E2 protein. FASEB J. 25: 2354-2361. books

Novakovic VA, Cullinan DC, Wakabayashi H, Fay P, Baleja JD, Gilbert GE. 2011. Membrane binding properties of the factor VIII C2 domain. Biochem J. 187-196. books

Henry GD, Corrigan DJ, Dineen JV, Baleja JD. 2010. Charge effects in the selection of NPF motifs by the EH domain of EHD1. Biochemistry 49: 3381-3392. books

Liu Y, Cherry JJ, Dineen JV, Androphy EJ, Baleja JD. 2009. Determinants of stability for the E6 protein of papillomavirus type 16. J Mol Biol. 386: 1123-1137.  books

Wei J, Liu Y, Bose K, Henry GD, Baleja JD. 2009. Disorder and structure in the Rab11 binding domain of Rab11 family interacting protein 2. Biochemistry 48: 549-557. Abstract in PubMed

Liu Y, Baleja JD. 2008. Structure and function of the papillomavirus E6 protein and its interacting proteins. Front Biosci 13: 121-134. books

Morstadt L, Bohm A, Yüksel D, Kumar K, Stollar BD, Baleja JD. 2008. Engineering and characterization of a single chain surrogate light chain variable domain. Protein Sci. 17: 458-465. Abstract in PubMed

Liu Y, Henry GD, Hegde RS, Baleja JD. 2007. Solution structure of the hDlg/SAP97 PDZ2 domain and its mechanism of interaction with HPV-18 papillomavirus E6 protein. Biochemistry 46: 10864-10874. books

Bose K, Yoder NC, Kumar K, Baleja, JD. 2007. The role of conserved histidines in the structure and stability of human papillomavirus type 16 E2 DNA binding domain.  Biochemistry 46: 1402-1411. books

Baleja JD, Cherry JJ, Liu Z, Gao H, Nicklaus MC, Voigt JH, Chen JJ, Androphy EJ. 2006. Identification of inhibitors to papillomavirus type 16 E6 protein based on three-dimensional structures of interaction proteins. Antiviral Res. 72: 49-59.  books

Wei J, Fain S, Harrison C, Feig LA, Baleja JD. 2006. Molecular dissection of Rab11 binding from coiled-coil formation in the Rab11-FIP2 C-terminal domain. Biochemistry 45: 6826-6834. books

Mukhopadhyay S, Langsetmo K, Stafford WF, 3rd, Henry, GD, Baleja JD, Sarkar S. 2004. Identification of a region of fast skeletal troponin T required for stabilization of the coiled-coil formation with troponin I. J Biol Chem. 280: 538-547. books

 

Liu Y, Liu Z, Androphy E, Chen J, Baleja JD. 2004. Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus. Biochemistry 43: 7421-7431. books

Apply to the Sackler School

apply

The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research