Recent Publications from the Aldridge Lab


Research Publications  Immunology Microbiology


Logsdon MM, Ho PY, Papavinasasundaram K, Richardson K, Cokol M, Sassetti CM, Amir A, Aldridge BB. 2017. A parallel adder coordinates Mycobacterial cell-cycle progression and cell-size homeostasis in the context of asymmetric growth and organization. Curr Biol. 27: 3367-3374. books

Cokol M, Kuru N, Bicak E, Larkins-Ford J, Aldridge BB. 2017. Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis. Sci Adv. 3:e1701881. books

Richardson K, Bennion OT, Tan S, Hoang AN, Cokol M, Aldridge BB. 2016. Temporal and intrinsic factors of rifampicin tolerance in mycobacteria. Proc Natl Acad Sic USA. 113: 8302-8307. Abstract in PubMed

Hayashi JM, Luo CY, Mayfield JA, Hsu T, Fukuda T, Walfield AL, Giffen SR, Leszyk JD, Baer CE, Bennion OT, Madduri A, Shaffer SA, Aldridge BB, Sassetti CM, Sandler SJ, Kinoshita T, Moody DB, Morita YS. 2016. Spatially distinct and metabolically active membrane domain in mycobacteria. Proc Natl Acad Sci USA. 113: 5400-5405.  Abstract in PubMed

Aldridge BB, Keren I, Fortune SM. 2014. The spectrum of drug susceptibility in Mycobacteria. Microbiol Spectr.  Abstract in PubMed

Sukumar N, Tan S, Aldridge BB, Russell DG. 2014. Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection. PLoS Pathog. 10: e1004394. Abstract in PubMed

Aldridge BB, Rhee KY. 2014. Microbial metabolomics: innovation, application, insight. Curr Opin Microbiol. 19: 90-96. Abstract in PubMed

Chao MC, Kieser KJ, Minami S, Mavrici D, Aldridge BB, Fortune SM, Alber T, Rubin EJ. 2013. Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria. PLoS Pathog, 9: e1003197. Abstract in PubMed

Wirth SE, Krywy JA, Aldridge BB, Fortune SM, Fernandez-Suarez M, Gray TA, Derbyshire KM. 2012. Polar assembly and scaffolding proteins of the virulence-associated ESX-1 secretory apparatus in mycobacteria.  Mol Microbiol. 83: 654-664. Abstract in PubMed

Aldridge BB, Fernandez-Suarez M, Heller D, Ambravaneswaran V, Irimia D, Toner M, Fortune SM. 2012. Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility. Science 335: 100-104. Abstract in PubMed

Aldridge BB, Gaudet S, Lauffenburger DA, Sorger PK. 2011. Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis. Mol Syst Biol. 22: 553.  Abstract in PubMed

Aldridge BB, Saez-Rodriguez J, Muhlich JL, Sorger PK, Lauffenburger DA.2009. Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling. PLoS Comput Biol. 5: e1000340. Abstract in PubMed

Albeck JG, Burke JM, Aldridge BB, Zhang M, Lauffenburger DA, Sorger PK. 2008. Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Mol Cell 30: 11-15. Abstract in PubMed

Aldridge BB, Burke JM, Lauffenburger DA, Sorger PK. 2006. Physicochemical modelling of cell signalling pathways. Nat Cell Biol.8: 1195-1203. Abstract in PubMed

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