Recent Publications from the Alcaide Lab

 

Research Publications Immunology

 

Nevers T, Salvador AM, Velazquez F, Ngwenyama N, Carrillo-Salinas FJ, Aronovitz M, Blanton RM, Alcaide P. 2017. Th1 effector T cells selectively orchestrate cardiac fibrosis in nonischemic heart failure. J Exp Med. Epub ahead of print. books

Salvador AM, Moss ME, Aronovitz M, Mueller KB, Blanton RM, Jaffe IZ, Alcaide P. 2017. Endothelial mineralocorticoid receptor contributes to systolic dysfunction induced by pressure overload without modulating cardiac hypertrophy or inflammation. Physiol Rep. 5 (12).  books

Salvador AM, Nevers T, Velázquez F, Aronovitz M, Wang B, Abadía Molina A, Jaffe IZ, Karas RH, Blanton RM, Alcaide P. 2016. Intercellular adhesion molecule 1 regulates left ventricular leukocyte infiltration, cardiac remodeling, and function in pressure overload-induced heart failure. J Am Heart Assoc. pii: e003126.  books

Schnoor M, Alcaide P, Voisin MB, van Buul JD. 2016. Recruitment of immune cells into inflamed tissues: Consequences for endothelial barrier integrity and tissue functionality. Mediators Inflamm. 2016: 1561368.  books

Velázquez F, Grodecki-Pena A, Knapp A, Salvador AM, Nevers T, Croce KJ, Alcaide P. 2015. CD43 functions as an E-selectin ligand for Th17 cells in vitro and is required for rolling on the vascular endothelium and Th17 cell recruitment during inflammation in vivo. J Immunol. 196: 1305-1316.  books

Schnoor M, Alcaide P, Voisin MB, van Buul JD. 2015. Crossing the vascular wall: Common and unique mechanisms exploited by different leukocyte subsets during extravasation. Mediators Inflamm. 2015: 946509. books

Bou Ghanem EN, Clark S, Roggensack SE, McIver SR, Alcaide P, Haydon PG, Leong JM. 2015. Extracellular adenosine protects against Streptococcus pneumoniae lung infection by regulating pulmonary neutrophil recruitment. PLoS Pathog. 11: e1005126.  books

Nevers T, Salvador AM, Grodecki-Pena A, Knapp A, Velazquez F, Aronovitz M, Kapur NK, Karas RH, Blanton RM, Alcaide P. 2015. Left Ventricular T Cell Recruitment Contributes to the Pathogenesis of Heart Failure. Circ Heat Fail. 8: 776-787. books

Massaad MJ, Oyoshi MK, Kane J, Koduru S, Alcaide P, Nakamura F, Ramesh N, Luscinskas FW, Hartwig J, Geha RS. 2014. Binding of WIP to actin is essential for T cell actin cytoskeleton integrity and tissue homing. Mol Cell Biol. 34: 4343-4354.  books

Bene NC, Alcaide P, Wortis HH, Jaffe IZ. 2014. Mineralocorticoid receptors in immune cells: Emerging role in cardiovascular disease. Steroids 91: 38-45. books

Alcaide P, Martinelli R, Newton G, Williams MR, Adams A, Vincent PA, Luscinskas FW. 2012. p120-catenin prevents neutrophil transmigration independently of Rho A inhibition by impairing Src dependent VE-cadherin phosphorylation. Am J Physiol Cell Physiol. 303:C385-C395. Abstract in PubMed

Griffin GK, Newton G, Tarrio ML, Bu DX, Maganto-Garcia E, Azcutia V, Alcaide P, Grabie N, Luscinskas FW, Croce KJ, Lichtman AH. 2012. IL-17 and TNF-α sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation. J Immunol. 188: 6287-6299.  Abstract in PubMed

Alcaide P, Maganto-Garcia E, Newton G, Travers R, Croce KJ, Bu DX, Luscinskas FW, Lichtman AH. 2012. Difference in Th1 and Th17 lymphocyte adhesion to endothelium. J Immunol. 188: 1421-1430. Abstract in PubMed

Maganto-García E, Bu DX, Tarrio ML, Alcaide P, Newton G, Griffin GK, Croce KJ, Luscinskas FW, Lichtman AH, Grabie N. 2011. Foxp3+-inducible regulatory T cells suppress endothelial activation and leukocyte recruitment. J Immunol. 187: 3521-3529. Abstract in PubMed

Williams MR, Azcutia V, Newton G, Alcaide P, Luscinskas FW. 2011. Emerging mechanisms of neutrophil recruitment across endothelium. Trends Immunol. 32: 461-469. Abstract in PubMed

Koduru S, Kumar L, Massaad MJ, Ramesh N, Le Bras S, Ozcan E, Oyoshi MK, Kaku M, Fujiwara Y, Kremer L, King S, Fuhlbrigge R, Rodig S, Sage P, Carman C, Alcaide P, Luscinskas FW, Geha RS. 2010. Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking. Proc Natl Acad Sci USA 107: 16252-16256. Abstract in PubMed

Alcaide P, Lim YC, Luscinskas FW, Fresno M. 2010. Mucin AgC10 from Trypanosoma cruzi interferes with L-selectin-mediated monocyte adhesion. Infect Immun. 78:1260-1268. Abstract in PubMed

Jones TG, Hallgren J, Humbles A, Burwell T, Finkelman FD, Alcaide P, Austen KF, Gurish MF. 2009. Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells. J Immunol. 183: 5251-5260. Abstract in PubMed

Kasorn A, Alcaide P, Jia Y, Subramanian KK, Sarraj B, Li Y, Loison F, Hattori H, Silberstein LE, Luscinskas WF, Luo HR. 2009. Focal adhesion kinase regulates pathogen-killing capability and life span of neutrophils via mediating both adhesion-dependent and -independent cellular signals. J Immunol. 183: 1032-1043. Abstract in PubMed

Alcaide P, Auerbach S, Luscinskas FW. 2009. Neutrophil recruitment under shear flow: it's all about endothelial cell rings and gaps. Microcirculation 16: 43-57. Abstract in PubMed

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