William Bachovchin, PhD

William Bachovchin, PhD

Professor of Developmental, Molecular & Chemical Biology

 

Education

BS, Biology, Wake Forest University
PhD, Chemistry, California Institute of Technology
Postdoctoral Training, California Institute of Technology; Harvard Medical School

Location

Campus: Boston
Office: M&V 613A
Laboratory: M&V 607, 612, 613, ST702

Contact Information

Office Phone: 617-636-6881
Lab Phone: 617-636-6882
E-mail   Send an e-mail

Links

Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Biochemistry, Cell, Molecular & Developmental Biology, Pharmacology & Experimental Therapeutics

 

Research Synopsis

The research in my laboratory includes mechanistic studies of serine proteases, and drug design and discovery. We also conduct structural studies on a variety of topics, often in collaboration with other faculty. Our serine protease studies use NMR and mutagenesis to identify and evaluate key hydrogen bonding and electrostatic interactions within serine protease active sites. The drug discovery efforts focus on the development of a platform technology for discovering new inhibitors of serine protease and the rationale design of "smarter" synthetic agents for modulating disease processes.

 

Lab Members

Christina Deliyiannis, PhD Student in Pharmacology & Experimental Therapeutics Send an e-mail Lab Research Page
Barry Jones, Senior Research Associate Send an e-mail Lab Research Page
Jack Lai, Research Assistant Professor Send an e-mail Lab Research Page
Yuxin Liu, Senior Research Associate Send an e-mail  Lab Research Page
Sarah Poplawski, Senior Research Associate Send an e-mail
David Sanford, Research Assistant Professor Send an e-mail  Lab Research Page
Wengen Wu, Senior Research Associate Send an e-mail  Lab Research Page
Yuhong (Jo) Zhou, Laboratory Manager Send an e-mail  Lab Research Page

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research