Professor Emeritus of Integrative Physiology & Pathobiology
BS, Biology, University of Pittsburgh
MS, Developmental Biology, University of Pittsburgh
PhD, Developmental Biology, University of Virginia
Postdoctoral Training, Massachusetts General Hospital
Office: Jaharis 3
Laboratory: Jaharis 329 & 332
Office Phone: 617-636-6695
Lab Phone: 617-636-3957
Research Web Site
Cell, Molecular & Developmental Biology
I no longer accept dissertation students but I am an active participant in graduate education through teaching and committee service.
My laboratory studies a number of aspects of developmental biology, chiefly in the cornea of the embryonic chicken. One area of research involves a tissue-specific mechanism we have discovered in corneal epithelial (CE) cells that prevents UV light-induced and oxidative damage to nuclear DNA. CE cells have virtually no tumors, possibly due to this mechanism for preventing these types of damage. The other area of research involves corneal innervation which is necessary for transducing sensations of pain and maintaining the cornea in a healthy state. Thus, pathological conditions that interfere with innervation and nerve function can lead to chronic pain, ulceration, and even loss of transparency.
Kristin Olsson, Senior Research Assistant
Christopher Talbot, Senior Research Assistant