Theoharis Theoharides, MD, PhD

Haris

Professor of Integrative Physiology & Pathobiology

 

Education

BA, Biology & History of Medicine, Yale University
MS, MPhil, Immunology, Yale University
PhD, Pharmacology, Yale University
MD, Yale University

Location

Campus: Boston
Office: Jaharis 304F
Laboratory: Jaharis 304

Contact Information

Office Phone: 617-636-6866
Lab Phone: 617-636-6898
E-mail   Send an e-mail

Links

Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Biochemistry, Pharmacology & Experimental Therapeutics

 

Research Synopsis

Our laboratory investigates the mechanism of selective secretion of cytokines and other pro-inflammatory molecules from mast cells. We have shown for the first time that mast cells can be activated by corticotropin-releasing hormone (CRH), the first molecule generated under stress, and by interleukin-1. CRH-activated mast cells lead to disruption of the gut-blood-brain barriers and thus contribute to brain inflammation. This process may participate in the pathophysiology of many diseases that worsen or precipitate under stress.

 

Lab Members

Mona Bawazeer, PhD Student in Pharmacology & Experimental Therapeutics Send an e-mail  Lab Research Page
Amanda Gross, PhD Student in Pharmacology & Experimental Therapeutics  Send an e-mail  Lab Research Page
Arti Patel, Postdoctoral Scholar Send an e-mail  Lab Research Page
Alexandra Taracanova, PhD Student in Pharmacology & Experimental Therapeutics Send an e-mail  Lab Research Page
Eirini Tsilioni, Postdoctoral Scholar Send an e-mail

Apply for 2017 Admission

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The priority application deadline for PhD programs is December 1, 2016.