Stephen Bunnell, PhD

Stephen Bunnell, PhD

Associate Professor of Immunology



BA, Biological Sciences, Cornell University
PhD, Biology, Harvard University
Postdoctoral Training, National Institutes of Health, Bethesda


Campus: Boston
Office: Jaharis 523B
Laboratory: Jaharis 524

Contact Information

Office Phone: 617-636-2174
Lab Phone: 617-636-2779
E-mail   Send an e-mail


Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs



Research Synopsis

We are interested in the signaling complexes that control T cell differentiation and activation. Using advanced imaging techniques we examine the assembly and localization of these complexes in living T cells. The composition of these structures varies dynamically in a fashion that reflects the physiological constraints on T cell activation. We have shown that these structures cannot persist in the absence of any of several critical proteins. These proteins are therefore likely to form a cooperatively assembled core complex upon which complete signaling complexes are built. Finally, we have found that these complexes change in localization over time. We are currently defining the components of the core complex and are testing how changes in localization affect the generation of signals uniquely required for T cell activation.


Lab Members

Keith Eidell, PhD Student in Immunology Send an e-mail  Lab Research Page
Frank Scangarello, MD, PhD Student in Immunology Send an e-mail  Lab Research Page
Michelle Sodipo, Research Technician Send an e-mail 

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research