Pamela Yelick, PhD

pam yelick

Professor of Oral Pathology

 

Education

BA, Biochemistry, Smith College
PhD, Biology, Tufts University
Postdoctoral Training, Dana Farber Cancer Institute; Harvard University

Location

Campus: Boston
Laboratory: M&V 824

Contact Information

Office Phone: 617-636-2430
Lab Phone: 617-636-4011
E-mail   Send an e-mail

Links

Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Cell, Molecular & Developmental Biology, Genetics, Pharmacology

 

Research Synopsis

Our research focuses on mineralized tissue – skeletal and craniofacial - development, homeostasis, disease and regeneration. Two main approaches are used: one using principles of tissue engineering (TE) for regenerative medicine and dentistry; and another using zebrafish as models for human mineralized tissue diseases. Our TE studies use post-natal dental stem cells harvested from extracted wisdom teeth and seeded onto biodegradable scaffolds, which are then implanted in in vivo animal models, to regenerate organized tooth crowns, periodontal tissues, and whole teeth. Using the developmental zebrafish model, we use a forward genetic mutagenesis approach combined with an in vivo mineralized tissue stain, to identify craniofacial and skeletal mutants. We believe that the synergistic nature of these combined approaches provide a unique opportunity to identify and functionally characterize genes regulating craniofacial and skeletal development and regeneration, and to test them in clinically relevant model systems.

 

Lab Members

Mohammed Bahrashi, DMD Student  Send an e-mail 
Emily Chen, Zebrafish Techincian Send an e-mail
Alex Cintolo, Senior Zebrafish Technician Send an e-mail 
Shaina Colón, Zebrafish Technician Send an e-mail 
Yvonne Chou, Zebrafish Technician Send an e-mail 
Quan Diep, Laboratory Administrator Send an e-mail 
Melissa LaBonty, PhD Student in Cell, Molecular & Developmental Biology Send an e-mail Lab Research Page
Sarah Liu, Graduate Research Intern Send an e-mail 
Sara Rudolph, Research Technician Send an e-mail 
Martin Serrano, Zebrafish Technician Send an e-mail 
Elizabeth Smith, Postdoctoral Scholar Send an e-mail Lab Research Page
Lauren Weinstock, Zebrafish Techinican Send an e-mail 
Weibo Zhang, Research Associate Send an e-mail  Lab Research Page

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February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development