Pamela Yelick, PhD

pam yelick

Professor of Oral Pathology

 

Education

BA, Biochemistry, Smith College
PhD, Biology, Tufts University
Postdoctoral Training, Dana Farber Cancer Institute; Harvard University

Location

Campus: Boston
Laboratory: M&V 824

Contact Information

Office Phone: 617-636-2430
Lab Phone: 617-636-4011
E-mail   Send an e-mail

Links

Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Cell, Molecular & Developmental Biology, Genetics, Pharmacology & Experimental Therapeutics

 

Research Synopsis

My research on craniofacial and dental tissue development and regeneration uses two approaches.  I use the principles of tissue engineering, using post-natal epithelial and mesenchymal dental stem cells, seeded onto biodegradable scaffolds and implanted in an in vivo model, to regenerate organized tooth crowns, periodontal tissues, and whole teeth.  My laboratory also exploits the developmental model of the zebrafish, using a mutagenesis approach combined with an in vivo mineralized tissue stain, to identify craniofacial, and primary and replacement tooth mutants.  The synergistic effects of these two approaches provide a unique opportunity to identify genes regulating craniofacial and replacement tooth formation, and to test them in clinically relevant model systems.

 

Lab Members

Viktoria Andreeva, Research Associate Send an e-mail  Lab Research Page
Leah DeFrancesco, Laboratory Manager Send an e-mail   Lab Research Page
Melissa LaBonty, PhD Student in Cell, Molecular & Developmental Biology Send an e-mail Lab Research Page
Nelson Monteiro, Postdoctoral Scholar Send an e-mail 
Elizabeth Smith, PhD Student in Cell, Molecular & Developmental Biology Send an e-mail Lab Research Page
Weibo Zhang, Research Associate Send an e-mail  Lab Research Page

Application for 2015 Admission

The application for 2015 admissions will be available soon.