Noorjahan Panjwani, PhD

Noorjahan Panjwani, PhD

Professor of Ophthalmology

 

Education

BS, Biochemistry, Karachi University
MS, Biochemistry, Strathclyde University
PhD, Biochemistry, Oxford University
Postdoctoral Training, Harvard Medical School

Location

Campus: Boston
Office: South Cove 7
Laboratory: South Cove 7

Contact Information

Office Phone: 617-636-6776
Lab Phone: 617-636-3828
E-mail   Send an e-mail

Links

Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Cell, Molecular & Developmental Biology, Immunology

 

Research Synopsis

We study the role of carbohydrate-binding proteins, specifically galectins, in the pathogenic mechanisms corneal infections and various aspects of wound healing such as angiogenesis, inflammation and development of scar tissue. Studies from my laboratory have shown that a specific member of galectin family, glaectin-3, plays a role in events which mediate angiogenesis, corneal epithelial sheet migration and development of corneal scarring. Our goal is to delineate molecular mechanisms by which galectin-3 modulates fibrosis and to develop galectin-based dual-benefit drugs to control both neovascularization and fibrosis of ocular tissues. In another study, we are investigating the role of another member of galectin family, galectin-8, in the regulation of corneal infection and inflammation. The goal of this project is to investigate our overarching hypothesis that galectin-8 regulates the outcome of Pseudomonas keratitis by modulating the function of toll-like receptors and inflammasomes. All projects in the lab have a solid basic science component to understand cell biological, immunological and biochemical mechanisms of wound healing and infection, and are disease-oriented with a focus on translational research to find better, novel ways to treat blinding diseases of the eye.

 

Lab Members

Zhiyi Cao, Senior Research Associate Send an e-mail  Lab Research Page
Abdulraouf Ramadan, Senior Research Associate  Send an e-mail

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development