Miguel Stadecker, MD, PhD

Miguel Stadecker, MD, PhD

Professor of Integrative Physiology & Pathobiology

 

Education

BA, National School Nr. 8
MD, University of Buenos Aires School of Medicine
PhD, Immunology, Tufts University
Postdoctoral Training, Harvard University

Location

Campus: Boston
Office: Jaharis 501J
Laboratory: Jaharis 501

Contact Information

Office Phone: 617-636-6732
Lab Phone: 617-636-2979
E-mail   Send an e-mail

Links

Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Immunology

 

Research Synopsis

My laboratory studies schistosomiasis, a disease caused by parasitic helminths of the genus Schistosoma, suffered by more than 200 million people throughout the world. The main pathology in schistosomiasis is a host CD4 T lymphocyte-mediated granulomatous inflammation against parasite eggs, which in the case of the species Schistosoma mansoni, takes place in the liver and intestines. Disease severity varies considerably, both in the human patient population, as well as among mouse strains in an experimental murine model. Our goal is to understand the role and interplay of CD4 T cell subpopulations in shaping the immunopathology in schistosomiasis, with emphasis on Th17 cells that mediate the severe form of disease. Current emphasis is placed on understanding the mechanism by which dendritic cell C-type lectin receptors, capable of sensing parasite eggs, can stimulate the secretion of proinflammatory cytokines that promote the development of pathogenic Th17 cells.

 

Lab Members

Parisa Kalantari, Research Assistant Professor Send an e-mail
Emily Miller, Research Technician  Send an e-mail

Apply to the Sackler School

apply

The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research