Martin Beinborn, PhD

Martin Beinborn, MD

Assistant Professor of Medicine

 

Education

BA, Language and Science, Städt Gymnasium, Langenberg
MD, Düsseldorf University
Postdoctoral Training, Harvard Medical School

 

Location

Campus: Boston
Office: Tupper, 7th Floor
Laboratory: Tupper, 7th Floor

Contact Information

Office Phone: 617-636-7740
Lab Phone: 617-636-8407
E-mail   Send an e-mail

 

Graduate Programs

Pharmacology

 

Research Synopsis

I am a molecular pharmacologist/endocrinologist with a primary interest in G-protein coupled receptors. These seven transmembrane domain proteins reside on the cell surface and are considered a major target of current drug discovery efforts. Research in my laboratory focuses on the mechanisms that enable high-affinity ligand-receptor interactions, as well as ligand-induced stimulation of intracellular signaling. As model systems to explore these processes, the specific receptors for two distinct types of peptide hormones are being studied, (i) cholecystokinin/gastrin (which are involved in multiple functions both in the gastrointestinal tract and in the central nervous system) and (ii) glucagon-like peptides (incretins/neurotransmitters that play an important physiological role in regulating blood glucose homeostasis, intestinal nutrient resorption, and food intake). Among these, the receptor for glucagon-like peptide-1 is of particular interest given its potential for the drug or gene therapy of diabetes and obesity.

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research