Linden Hu, MD

Linden Hu, MD

Professor of Molecular Biology & Microbiology



AB, Human Biology, Brown University
MD, Brown University


Campus: Boston
Office: South Cove 802
Laboratory: South Cove 8

Contact Information

Office Phone: 617-636-8498
Lab Phone: 617-636-7613
E-mail   Send an e-mail


Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Immunology, Molecular Microbiology


Research Synopsis

My laboratory studies host-pathogen interactions of the organism Borrelia burgdorferi. I am interested in both how the organism responds and adapts to its changing environments, as well as the impact of the host immune response to B. burgdorferi on manifestations of disease. There are currently three major projects on-going in my laboratory. The projects are: 1) Co-opting of host proteases by Borrelia burgdorferi: utilization of host inflammatory responses in the pathogenesis of Lyme arthritis, 2) The role of the oligopeptide permease (Opp) transporter of B. burgdorferi in environmental sensing, signaling and adaptation, and 3) Reduction of vector and reservoir competence for carriage of Borrelia burgdorferi: development of a vaccine for mice in wild-life settings.


Lab Members

Marisha Collins, Postdoctoral Scholar Send an e-mail  Lab Research Page
Louis Cornacchione, PhD Student in Molecular Microbiology  Send an e-mail  Lab Research Page
Aurélie Kern, Postdoctoral Scholar Send an e-mail Lab Research Page
Maureen Lundt, Clinical Coordinator  Send an e-mail 
Sujatha Muralidharan, Postdoctoral Scholar Send an e-mail Lab Research Page
Joshua Norville, Research Coordinator Send an e-mail 
Tanja Petnicki-Ocwieja, Assistant Professor Send an e-mail  Lab Research Page
James Phelan, PhD Student in Molecular Microbiology - MERGE-ID Send an e-mail  Lab Research Page
Urmila Powale, PhD Student in Immunology  Send an e-mail  Lab Research Page
Meghan Ramsey, Postdoctoral Scholar Send an e-mail Lab Research Page
Bijaya Sharma, Postdoctoral Scholar Send an e-mail 

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research