Lidija Covic, PhD

Lidija Covic, PhD

Assistant Professor of Medicine

 

Education

BS, Genetics, University of Manitoba
MS, Biophysics, University of Toronto
PhD, Biology, York University
Postdoctoral Training, Tufts University School of Medicine

Location

Campus: Boston
Office: 75 Kneeland, 10th Floor
Laboratory: 75 Kneeland, 10th Floor

Contact Information

Office Phone: 617-636-4665
Lab Phone: 617-636-8486
E-mail   Send an e-mail

Links

Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Cell, Molecular & Developmental Biology

 

Research Synopsis

In the Covic laboratory, we study a novel class of cell surface proteins known as protease-activated receptors. These receptors include the major thrombin receptor of blood vessels and platelets as well as receptors that are involved in cancer invasion and metastasis. The first member of the protease-activated receptor family, PAR1, has been identified as an oncogene and its expression correlates strongly with invasive and metastatic processes of cancer cells from breast, melanoma and ovarian tumors. In addition, we study the downstream signaling molecule, the angiogenesis factor Cyr61, in the malignant progression of breast cancer. Cyr61 was identified as a marker for poor prognosis in a recent large breast cancer study.

 

Lab Members

Nga Nguyen, Research Assistant Send an e-mail   Lab Research Page
James Parkins, Visiting Scholar Send an e-mail  
Layla Van Doren, Oncology Fellow Send an e-mail  

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research