K Eric Paulson, PhD

K. Eric Paulson, PhD

Research Assistant Professor of Developmental, Molecular & Chemical Biology

 

Education

AB, Biochemistry, University of California, Berkeley
PhD, Biochemistry, University of California, Davis
Postdoctoral Training, The Rockefeller University

 

Location

Campus: Boston
Laboratory: Jaharis 601

Contact Information

Office Phone: 617-636-4776
Lab Phone: 617-636-6851
E-mail   Send an e-mail

 

Graduate Programs

Biochemistry

 

Research Synopsis

In collaboration with Amy Yee, we are investigating new molecular mechanisms of tumor suppression to design new diagnostic and therapeutic strategies in breast cancer. We combine investigations in signaling pathways and in transcriptional regulation with directed clinical studies. We focus on the Wnt pathway, which has emerged as a major pathway in breast and other cancers, and HBP1, as a transcriptional repressor that is also a suppressor of Wnt signaling. HBP1 mutations are clinically associated with invasive breast cancer. Thus, HBP1 is a new tumor suppressor gene with clinical and molecular impact on invasive breast cancer.

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research