Johanna Seddon, MD

Johanna Seddon, MD

Professor of Ophthalmology



BS, Chemistry & Physics, University of Pittsburgh
ScM, Epidemiology, Harvard School of Public Health
MD, University of Pittsburgh School of Medicine



Campus: Boston

Contact Information

Office Phone: 617-636-9000
E-mail   Send an e-mail


Graduate Programs

Clinical & Translational Science


Research Synopsis

My research interests include the etiology, prevention and treatment of macular degeneration, hereditary retinal disorders, retinal vascular disorders, and degenerative disorders. Our research team studies the effect of lifestyle and genetic and biochemical biomarkers for age-related and younger onset macular degenerations as well as macular dystrophies. I have found that the dietary antioxidants lutein and zeaxanthin as well as fat intake, omega-3 fatty acids, and obesity influence the risk of macular degeneration and progression to the advanced stages. We discovered 15 different genetic variants including some rare and highly penetrant genetic variants which are strongly associated with the macular degeneration in families. We developed comprehensive risk prediction models and an on-line risk calculator. Current work is focused on identifying genetic associations and interactions with non-genetic risk factors and sub-phenotypes of the disease.

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research