Jamie Maguire, PhD


Assistant Professor of Neuroscience



BA, BS, Art History & Neuroscience, University of Pittsburgh
PhD, Neuroscience, George Washington University
Postdoctoral Training, University of California, Los Angeles


Campus: Boston
Office: South Cove 205
Laboratory: South Cove 201

Contact Information

Office Phone: 617-636-3595
Lab Phone: 617-636-3815
E-mail   Send an e-mail


Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Neuroscience, Pharmacology


Research Synopsis

Research in my lab focuses on the regulation of GABAA receptors (GABAARs), which mediate the majority of inhibitory synaptic transmission in the central nervous system. Our goal is to understand how GABAARs and therefore GABAergic inhibition, is regulation under both physiological and pathological conditions. We use a wide variety of approaches, ranging from electrophysiology to behavior. A particular focus of the lab is the GABAergic regulation of the hypothalamic-pituitary-adrenal (HPA) axis, which mediates the body's response to stress. Stress is a common trigger for many disorders, probably due to the impact of stress hormones on neuronal excitabilility. The major output of the stress response, neurons in the paraventricular nucleus (PVN) of the hypothalamus, are under GABAergic control. Our goal is to determine the nature of GABAAR regulation of the PVN and to understand how dysfunction affects the pathophysiology of neurologicial and neuropsychiatric disorders.


Lab Members

Aishwarya Kulkarni, MS Student in Pharmacology & Drug Development Send an e-mail Lab Research Page
Laverne Melon, Postdoctoral Scholar Send an e-mail  Lab Research Page

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research