James Baleja, PhD

James Baleja, PhD

Associate Professor of Developmental, Molecular & Chemical Biology

 

Education

BSc, Biochemistry, University of Manitoba
MSc, Chemistry, University of Manitoba
PhD, Biochemistry, University of Alberta
Postdoctoral Training, Harvard Medical School

Location

Campus: Boston
Office: M&V 614
Laboratory: M&V 614

Contact Information

Office Phone: 617-636-6872
Lab Phone: 617-636-6873
E-mail   Send an e-mail

Links

Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Biochemistry, Cell, Molecular & Developmental Biology

 

Research Synopsis

My laboratory uses NMR (nuclear magnetic resonance) spectroscopy and other biophysical methods to determine high-resolution models for proteins, to quantify molecular interactions, and to measure metabolite levels in tissues and cells. Molecular agents are designed from these 3-dimensional structures to help develop inhibitor s to major human diseases such as cervical cancer and thrombosis. More specifically, we are examining proteins of the human papillomavirus (HPV), which is the causal agent for both the common wart and cervical cancer. We also are studying the Eps15-homology (EH) domain from proteins that link intracellular molecular trafficking to signal transduction with specific applications to epithelial cancers such as squamous cell carcinoma.

 

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research