Jake (Jinkun) Chen, DDS, PhD

Jake (Jinkun) Chen, DDS, PhD

Professor of General Dentistry



DDS, Jiao Tong University
DMD, Tufts University School of Dental Medicine
PhD, Biomedical Sciences, University of Toronto


Campus: Boston
Office: Dental, 6th Floor
Laboratory: Dental, 6th Floor

Contact Information

Office Phone: 617-636-2729
Lab Phone: 617-636-0341
E-mail   Send an e-mail


Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Cell, Molecular & Developmental Biology 


Research Synopsis

Our laboratory focuses on three research areas: 1. Gene expression and regulation in bone formation and tooth development using transgenics, lentiviral infection, signaling transduction pathway and small RNA approaches; 2. Stem cells and transcription factors in bone tissue engineering and regeneration using gene-therapy and double labeled cell-based approaches to repair dental and craniofacial tissue defects; 3. Translational studies including bone metastasis of breast cancer cells, bisphosphonate-associated osteonecrosis of the jaws and osseointegration of titanium implants

Lab Members

Tong Chen, Visiting Scientist  
Kevin Hu, Visiting Scientist 
Wei Qiu, Visiting Scientist 
Yu Shi, Visiting Scientist  Send an e-mail
Yin Tang, Visiting Scientist Send an e-mail
Qisheng Tu, Associate Professor  Send an e-mail  Lab Research Page
Paloma Valverde, Consultant Send an e-mail 
Xingwen Wu, Visiting Scientist
Xiaofang Zhu, Visiting Scientist Send an e-mail

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research