F Rob Jackson, PhD

Rob Jackson

Professor of Neuroscience

 

Education

BA, Biology, Sonoma State College
PhD, Biology & Genetics, University of California, Los Angeles
Postdoctoral Training, Albert Einstein College of Medicine; The Rockefeller University

Location

Campus: Boston
Office: Stearns 329
Laboratory: Arnold 305

Contact Information

Office Phone: 617-636-6752
Lab Phone: 617-636-3680
E-mail   Send an e-mail

Links

Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Genetics, Neuroscience

 

Research Synopsis

Research in the Jackson lab is currently focused on defining the neural circuits mediating behavior. We are particularly interested in glial-neuron communication and its relevance to behavior, with a special emphasis on sleep and circadian behavior. Genetic or environmental insults affecting the circadian system result in alterations of sleep, seasonal depression and other neurological disorders. Our lab employs classical genetic approaches combined with genome-wide expression profiling, cellular imaging and behavioral studies to understand the neural circuitry controlling rhythmic behaviors. We have shown that glial astrocytes of the Drosophila brain are critical for normal rhythmicity and that they regulate the circadian neuronal circuitry (Suh and Jackson, 2007 Abstract in PubMed; Ng et al, 2011 Abstract in PubMed). In recent studies, we have performed genome-wide translational profiling of adult fly astrocytes (Huang et al, 2015 Abstract in PubMed) and conducted RNA interference (RNAi)-based genetic screens to identify specific glial factors that are required for circadian behavior or sleep. The genetic studies demonstrated that glial secretion mechanisms are critical for normal rhythmicity (Ng and Jackson, 2015 Abstract in PubMed)and revealed a number of small secreted glial proteins that regulate sleep or circadian behavior. Our work is currently focused on understanding the cellular pathways through which such glial factors regulate behavior.

 

Lab Members

Lauren Crowe, Postdoctoral Scholar Send an e-mail Lab Research Page
Mary Roberts, Research Technican Send an e-mail
Samantha You, PhD Student in Neuroscience Send an e-mail  Lab Research Page
Amy Yu, Postdoctoral Scholar Send an e-mail  Lab Research Page

Apply for 2017 Admission

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The priority application deadline for PhD programs is December 1, 2016.