Ewelina Bolcun-Filas

Assistant Professor of Medicine

 

Education

MSc, Biology, Jagiellonian University
PhD, Developmental Biology, Georg-August-Universität Göttingen
Postdoctoral Training, MRC Human Genetics Unit; Cornell University

 

Location

Campus: The Jackson Laboratory, Bar Harbor, ME


Contact Information

Office Phone: 207-288-6985

E-mail   Send an e-mail

 

Graduate Programs

Genetics

 

Research Synopsis

Germ cells are the only cell type that must endure extensive DNA damage in the form of programmed meiotic double-strand breaks (DSBs) during their normal development. Paradoxically, the absence of DSBs during meiosis as well as persisting unrepaired breaks are detrimental and typically result in meiotic arrest and infertility. Our research aims to understand the molecular mechanisms controlling the development of healthy gametes and how misregulation of these mechanisms can lead to reproductive disorders.We are also interested in how chemotherapy affects these checkpoints and leads to premature ovarian failure and infertility.

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research