Emmanuel Pothos, PhD

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Associate Professor of Integrative Physiology & Pathobiology

 

Education

BA, Experimental Psychology, American College of Athens
BA, Philosophy, University of Athens
MA, PhD, Neuroscience, Princeton University
Postdoctoral Training, Columbia University

Location

Campus: Boston
Office: M&V 317
Laboratory: M&V 3

Contact Information

Office Phone: 617-636-6778
Lab Phone: 617-636-3483
E-mail   Send an e-mail

Links

Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Neuroscience, Pharmacology & Experimental Therapeutics

 

Research Synopsis

Our laboratory studies cellular and molecular mechanisms of synaptic neurotransmission in the midbrain and its catecholaminergic projections because of our interest in the neurochemistry and molecular biology of catecholamine-related disorders. The current focus is on the study of the plasticity of CNS catecholamine quantal size as it relates to normal function and the pathogenesis, development and symptoms of feeding/body weight disorders (like dietary obesity), drug addiction, psychotic disorders and movement disorders (like Parkinson's disease). Contrary to previous dogmas, quantal size (the amount of neurotransmitter released per vesicle during exocytosis) is not invariant in CNS catecholamine systems and offers us the opportunity to pharmacologically intervene at the presynaptic level in order to block or inhibit a catecholamine-related abnormality.

 

Lab Members

Caroline Appel, MS Student in Pharmacology & Drug Development   Send an e-mail Lab Research Page

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research