Ekaterina Heldwein, PhD

Ekaterina Heldwein, PhD

Associate Professor of Molecular Biology & Microbiology

 

Education

MS, Chemistry, Lomonosov Moscow State University
PhD, Biochemsitry, Oregon Health & Sciences University
Postdoctoral Training, Oregon Health & Sciences University; Harvard Medical School

Location

Campus: Boston
Office: Arnold 611C
Laboratory: Arnold 611

Contact Information

Office Phone: 617-636-0858
Lab Phone: 617-636-0474
E-mail   Send an e-mail

Links

Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Biochemistry, Cell, Molecular & Developmental Biology, Molecular Microbiology

 

Research Synopsis

The work in my laboratory focuses on structural analysis of the complex cell-entry machinery of herpesviruses with the ambition to develop a "molecular movie" illustrating successive steps during entry. Herpesviruses are a family of human pathogens, such as Herpes Simplex virus, cytomegalovirus, and Epstein-Barr virus, that infect their hosts for life, causing cold sores, blindness, encephalitis, cancers, and life-threatening conditions in immunocompromised individuals. Knowing the detailed mechanism of their entry into cells may lead to the design of antiviral therapeutics. In our research, we use X-ray crystallography with contributions from other biophysical and biochemical techniques.

 

Lab Members

Janna Bigalke, Postdoctoral Scholar Send an e-mail  Lab Research Page
Heidi Burke, MERGE-ID PhD Student in Molecular Microbiology Send an e-mail  Lab Research Page
Rebecca Cooper, Postdoctoral Scholar  Send an e-mail  Lab Research Page
Andrea Koenigsberg, PhD Student in Molecular Microbiology   Send an e-mail  Lab Research Page
Claire Metrick, PhD Student in Biochemistry Send an e-mail  Lab Research Page
Henry Rogalin, PhD Student in Biochemistry Send an e-mail  Lab Research Page

Application for 2015 Admission

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The deadline for PhD programs is December 15, 2014.