Ekaterina Heldwein, PhD

Ekaterina Heldwein, PhD

Associate Professor of Molecular Biology & Microbiology



MS, Chemistry, Lomonosov Moscow State University
PhD, Biochemsitry, Oregon Health & Sciences University
Postdoctoral Training, Oregon Health & Sciences University; Harvard Medical School


Campus: Boston
Office: Arnold 611C
Laboratory: Arnold 611

Contact Information

Office Phone: 617-636-0858
Lab Phone: 617-636-0474
E-mail   Send an e-mail


Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Biochemistry, Cell, Molecular & Developmental Biology, Molecular Microbiology


Research Synopsis

The work in my laboratory focuses on structural analysis of the complex cell-entry machinery of herpesviruses with the ambition to develop a "molecular movie" illustrating successive steps during entry. Herpesviruses are a family of human pathogens, such as Herpes Simplex virus, cytomegalovirus, and Epstein-Barr virus, that infect their hosts for life, causing cold sores, blindness, encephalitis, cancers, and life-threatening conditions in immunocompromised individuals. Knowing the detailed mechanism of their entry into cells may lead to the design of antiviral therapeutics. In our research, we use X-ray crystallography with contributions from other biophysical and biochemical techniques.


Lab Members

Elizabeth Draganova, Postdoctoral Scholar Send an e-mail  Lab Research Page
Xuanzong Guo, Senior Research Technician Send an e-mail 
Adam Hilterbrand, Postdoctoral Scholar Send an e-mail Lab Research Page
Andrea Koenigsberg, PhD Student in Molecular Microbiology   Send an e-mail  Lab Research Page
Claire Metrick, PhD Student in Biochemistry Send an e-mail  Lab Research Page
Anshumali Mittal, Postdoctoral Scholar Send an e-mail Lab Research Page
Michael Thorsen, PhD Student in Cell, Molecular & Developmental Biology  Send an e-mail Lab Research Page
Ellen White, Postdoctoral Scholar Send an e-mail  Lab Research Page

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research