Ekaterina Heldwein, PhD

Ekaterina Heldwein, PhD

Professor of Molecular Biology & Microbiology



MS, Chemistry, Lomonosov Moscow State University
PhD, Biochemistry, Oregon Health & Sciences University
Postdoctoral Training, Oregon Health & Sciences University; Harvard Medical School


Campus: Boston
Office: Arnold 611C
Laboratory: Arnold 611

Contact Information

Office Phone: 617-636-0858
Lab Phone: 617-636-0474
E-mail   Send an e-mail


Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Cell, Molecular & Developmental Biology, Molecular Microbiology


Research Synopsis

The work in my laboratory focuses on herpesviruses. These large, complex, and ancient viruses infect most of the world’s population for life and can cause a number of ailments ranging from cold sores to blindness, encephalitis, and cancers. Development of new therapeutic approaches to lessen the burden of herpesvirus diseases requires a deeper understanding of how herpesviruses manipulate their hosts. Research in my laboratory aims to answer three broad questions: How do herpesviruses enter cells to initiate infection? How are progeny virions assembled and released from the cells? How do virions move in infected cells? To gain deeper insight into molecular mechanisms of the herpesvirus life cycle, we harness the power of structural biology, biochemistry, biophysics and cell biology. Our long-term goal is to translate this resulting body of mechanistic knowledge to the discovery of new and effective antivirals.


Lab Members

Elizabeth Draganova, Postdoctoral Scholar Send an e-mail  Lab Research Page
Xuanzong Guo, Senior Research Technician Send an e-mail 
Adam Hilterbrand, Postdoctoral Scholar Send an e-mail Lab Research Page
Andrea Koenigsberg, PhD Student in Molecular Microbiology   Send an e-mail  Lab Research Page
Anshumali Mittal, Postdoctoral Scholar Send an e-mail Lab Research Page
Michael Thorsen, PhD Student in Cell, Molecular & Developmental Biology  Send an e-mail Lab Research Page
Ellen White, Postdoctoral Scholar Send an e-mail  Lab Research Page

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research