Chengkai Dai, MD, PhD

Assistant Professor of Medicine



MS, Pathophysiology, Tianjin Medical University
MD, Tianjin Medical University
PhD, Genes & Development, University of Texas Health Science Center, Houston
Postdoctoral Training, Whitehead Institute, MIT



Campus: The Jackson Laboratory, Bar Harbor, ME
Office: Bldg 33, 2135
Laboratory: Bldg 33, 2050

Contact Information

Office Phone: 207-288-6927
Lab Phone: 207-288-6927
E-mail   Send an e-mail


Graduate Programs



Research Synopsis

Our laboratory focuses on understanding the emerging roles of the heat-shock or stress response in human cancers and longevity. The stress response is an evolutionarily highly conserved adaptive mechanism that enhances cell survival in the face of a large variety of stressful insults from without and from within. In mammals, the master transcriptional regulator of this systemic cellular response is heat shock factor 1, HSF1, a pleiotropic molecule that coordinates a network of cellular pathways to fight stresses. One of the major functions of this stress response is to maintain proteome homeostasis under stressful conditions.

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research