Brian Schaffhausen, PhD

Brian Schaffhausen, PhD

Professor Emeritus of Developmental, Molecular & Chemical Biology



BS, Chemistry, Antioch College
PhD, Biochemistry, Brandeis University
Postdoctoral Training, Harvard Medical School


Campus: Boston
Office: Jaharis 606
Laboratory: Jaharis 601

Contact Information

Office Phone: 617-636-6868
Lab Phone: 617-636-6854
E-mail   Send an e-mail


Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Cell, Molecular & Developmental Biology, Genetics, Molecular Microbiology


Research Synopsis

I maintain an active research lab but no longer accept dissertation students.

We are interested in the biological events that make a cell a cancer cell and the biochemical consequences of protein phosphorylation. We start with murine polyomavirus, a small double-stranded DNA virus that causes a broad spectrum of tumors. Our virus studies provide leads for studying cellular signal transduction pathways. We are interested in both tumor suppressors that function to restrict cell growth as well as positive signaling molecules such as lipid and protein kinases. Our general approach is to combine genetic analysis with protein biochemistry. The range of our work extends from tumor studies to NMR structural analysis.


Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research