Bree Aldridge, PhD

Bree

Assistant Professor of Molecular Biology & Microbiology

 

Education

BS, Computer Engineering, Molecular & Cellular Biology, University of Arizona
PhD, Biological Engineering, MIT
Postdoctoral Training, Harvard School of Public Health

Location

Campus: Boston
Office: Arnold 511D
Laboratory: Arnold 511

Contact Information

Office Phone: 617-636-6703
Lab Phone: 617-636-0919
E-mail   Send an e-mail

Links

Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Immunology, Molecular Microbiology

 

Research Synopsis

Tuberculosis remains a threat to global health, killing ~2 million people every year. The causative agent of tuberculosis, Mycobacterium tuberculosis, is thought to infect one third of world’s population, sickening ~10 million people a year. Despite efforts to simplify treatment strategies, tuberculosis still requires months of multi-drug therapy to cure. We merge engineering and molecular approaches to develop quantitative descriptions of the determinants of mycobacterial stress tolerance and virulence. Our approach is motivated by our recent finding that the asymmetric growth pattern of mycobacteria creates subpopulations of cells with different growth parameters and tolerance to antibiotic treatment. We are building a multidisciplinary research group that couples quantitative single-cell measurements and mathematical modeling with the goal of shortening and simplifying treatment regimens against tuberculosis.

 

Lab Members

Geoffrey Gonzalez-Escobedo, Postdoctoral Scholar  Send an e-mail  Lab Research Page
Alexander Histed, PhD Student in Immunology Send an e-mail  Lab Research Page
Jonah Larkins-Ford, MERGE-ID PhD Student in Molecular Microbiology Send an e-mail Lab Research Page
Michelle Logsdon, PhD Student in Molecular Microbiology Send an e-mail  Lab Research Page
Brandon Phan, PREP Scholar  Send an e-mail Lab Research Page
Kirill Richardson, Research Technician Send an e-mail Lab Research Page
Amy Thurber, Postdoctoral Scholar Send an e-mail Lab Research Page

Apply for 2017 Admission

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The priority application deadline for PhD programs is December 1, 2016.