Athan Kuliopulos, MD, PhD


Professor of Medicine



BS, Biology, Rensselaer Polytechnic Institute
MD, PhD, Biochemistry, Johns Hopkins Medical School
Postdoctoral Training, Harvard Medical School


Campus: Boston
Office: 75 Kneeland, 10th Floor
Laboratory: 75 Kneeland, 10th Floor

Contact Information

Office Phone: 617-636-8482
Lab Phone: 617-636-8486
E-mail   Send an e-mail


Research Web Site  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Biochemistry, Cell, Molecular & Developmental Biology, Genetics


Research Synopsis

Protease-activated receptors (PARs) are a unique class of G protein-coupled receptors that play critical roles in cancer, inflammation, and vascular biology. The PARs are cleaved by thrombin, MMP-1 and other proteases to expose a new N-terminus that binds to the body of the receptor in an unusual intramolecular mode. A major interest of our research group is to study the molecular mechanism of protease activation of the PARs and the subsequent signaling in vascular cells and in cancer.


Lab Members

Laura Flynn, Clinical Research Coordinator Send an e-mail 
Emily Michael, PhD Student in Biochemistry Send an e-mail  Lab Research Page
Rajashree Rana, Postdoctoral Scholar Send an e-mail 
Andrew Shearer, PhD Student in Biochemistry Send an e-mail  Lab Research Page

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research