Amy Yee, PhD

Amy Yee, PhD

Professor of Developmental, Molecular & Chemical Biology



BS, Biochemistry, University of California, Berkeley
PhD, Biochemistry, University of California, Davis
Postdoctoral Training, The Rockefeller University


Campus: Boston
Office: Jaharis 614
Laboratory: Jaharis 601

Contact Information

Office Phone: 617-636-6850
Lab Phone: 617-636-6851
E-mail   Send an e-mail


Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Biochemistry, Cell, Molecular & Developmental Biology, Genetics, Pharmacology & Experimental Therapeutics


Research Synopsis

We are investigating new molecular mechanisms of tumor suppression to design new diagnostic and therapeutic strategies in breast cancer. We combine investigations in signaling pathways and in transcriptional regulation with directed clinical studies. We focus on the Wnt pathway, which has emerged as a major pathway in breast and other cancers, and HBP1, as a transcriptional repressor that is also a suppressor of Wnt signaling. HBP1 mutations are clinically associated with invasive breast cancer. Thus, HBP1 is a new tumor suppressor gene with clinical and molecular impact on invasive breast cancer.


Lab Members

Miriam Alamoudi, PhD Student in Pharmacology & Experimental Therapeutics  Send an e-mail Lab Research Page
Roaya Alqurashi, PhD Student in Pharmacology & Experimental Therapeutics   Send an e-mail Lab Research Page
K Eric Paulsen, Research Assistant Professor  Send an e-mail

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research